Pharm Meds: side/adv effects

diazepam, lorazepam, midazolam, chlordiazepoxide “lam”

side: sedation, amnesia, respiratory depression

buspirone

side: dizziness, nausea, headache (no sedation)

amitriptyline, imipramine

side: sedation, orthostatic hypotension, ANTICHOLINERGIC EFFECTS, arrythmias, sweating, seizures, SUICIDAL THOUGHTS/BEHAVIORS

lithium

NEPHROTOXICITY, FINE HAND TREMORS, POLYURIA, increased thirst, electrolyte imbalances, hypothyroidism, leukocytosis, gi upset, weight gain, fatigue

chlorpromazine, haloperidol, droperidol

side: EXTRAPYRAMIDAL SYMPTOMS, NEUROLEPTIC MALIGNANT SYNDROME, agranulocytosis, anticholinergic effects, orthostatic hypotension, sedation, seizures

disulfiram, naltrexone, acamprosate

promotes abstinence

buprenorphine, methadone

sedation, confusion, constipation, hypotension

ABUSE, ADDITION, LIFE-THREATENING RESPIRATORY DEPRESSION

acetaminophen

GI upset

HEPATOTOXICITY

ibuprofen, naproxen, ketorolac, indomethacin

GI upset, nephrotoxicity

GI BLEEDING, ULCERATION, PERFORATION, INC. RISK OF CARDIOVASCULAR THROMBOTIC EVENTS (MI, STROKE)

apirin

tinnitus, GI bleeding, GI upset, rash

abd. pain, salicylism, peptic ulcer disease, intestinal blood loss, reye’s syndrome, itchy rash, noise (tinnitus)

fentanyl, morphine, hydromorphone, oxycodone, hydrocodone

SEDATION, GI upset, (constipation), hypotension, urinary retention

LIFE THREATENING RESPIRATORY DEPRESSION, ADDICTION, ABUSE, NEONATAL OPIOID WITHDRAWL SYNDROME

valporic acid, divalproex sodium, valproate sodium

GI upset, thrombocytopenia

HEPATOTOXICITY, PANCREATITIS, FETAL RISK

monitor liver function, and CBC levels

carbamazepine, lamotrigine

BLOOD DYSCRASIAS, (anemia, leukopenia, thrombocytopenia), vision issues, (nystagmus, diplopia)

STEVENS-JOHNSON SYNDROME, TOXIC EPIDERMAL NECROLYSIS, APLASTIC ANEMIA, AGRANULOCYTOSIS

Bupropion

insomnia, headache, GI upset, weight loss, agitation, seizures

SUICIDAL THOUGHTS/BEHAVIORS

phenelzine, tranylcypromine, isocarboxazid, selegiline

side: agitation/anxiety, orthostatic hypotension

SUICIDAL THOGUHTS/BEHAVIORS, HYPERTENSIVE CRISIS

—> do not consume tyramine rich foods

pregabalin, gabapentin

Side: dizziness, drowsiness, dry mouth, edema, potential for abuse

sumatriptan

side: dizziness/vertigo, warm/tingling sensation

CARDIOVASCULAR THROMBOTIC EVENTS, GI BLEEDING, ULCERATION, PERFORATION

donepezil

side: headaches, diarrhea, nausea

carbidopa/levodopa

side: dyskinesia(tics), orthostatic hypotension, dark urine and sweat, nausea/ vomiting, psychosis

—> avoid high protein meals and they dec medication effectiveness

phenytoin, fosphenytoin

side: gingival hyperplasia, vision issues, dizziness, GI upset

—> dec effectiveness of oral contraceptives