Leukemia and Lymphoma Lecture Notes

A collection of vocabulary flashcards covering key terms and concepts related to leukemia, lymphoma, and hematological abnormalities.

Leukemia

A type of cancer that affects blood and bone marrow, characterized by the overproduction of abnormal white blood cells.

Lymphoma

A group of blood cancers that develop from lymphocytes, a type of white blood cell.

Abnormal WBCs

White blood cells that exhibit unusual characteristics or functions, often indicative of a disease or disorder.

N:C ratio

The ratio of the size of the nucleus to the size of the cytoplasm in a cell; an important feature in identifying abnormal cells.

Atypical Lymphs

Lymphocytes that have abnormal morphology, indicating a possible pathological condition.

Toxic Granulation

An abnormal finding in neutrophils that indicates a response to infection or inflammation, characterized by the presence of coarse granules.

Döhle Bodies

Cytoplasmic inclusions in neutrophils that suggest a response to infection and are often seen with toxic granulation.

Howell Jolly Bodies

Nuclear remnants found in red blood cells, typically seen in conditions where the spleen is absent or dysfunctional.

Pappenheimer Bodies

Granules found in red blood cells that indicate abnormal iron metabolism, often associated with conditions like sideroblastic anemia.

Toxic Vacuoles

Vacuoles found in neutrophils during acute infections, indicating cellular distress or dysfunction.

Myeloblast

An immature precursor cell in the myeloid lineage that can develop into various types of granulocytes.

Promyelocyte

A stage of myeloid cell development that follows the myeloblast stage, typically featuring azurophilic granules.

Metamyelocyte

A later stage in myeloid cell development that is more mature than a promyelocyte and has a more condensed nucleus.

Differential Count

A laboratory test that involves counting and categorizing white blood cells in a sample to assess health and detect abnormalities.

Band Cell

An immature neutrophil characterized by a band-shaped nucleus, indicative of a response to infection or inflammation.