Clin. Chem. Mod. 1

Kernicterus is the abnormal accumulation of bilirubin in ________ — causes jaundice in infants:

Brain tissue.

Kidney tissue.

Liver tissue.

Heart tissue.

Brain tissue

How soon following acute abdominal pain due to pancreatitis is the serum amylase level expected to rise?

3–6 hours

1–2 hours

6–12 hours

12–24 hours

3–6 hours

A breakdown product of bilirubin metabolism that is produced in the colon from the oxidation of urobilinogen by microorganisms is:

Urobilin(ogen)

Porphobilinogen

Protoporphyrin

Stercobilinogen

Protoheme.

Urobilin(ogen)

Which of the following is an autosomal recessive genetic disorder that begins in the pancreas and leads to lung disease?

Respiratory distress syndrome

Chronic obstructive pulmonary disease

Cystic fibrosis

Tuberculosis

Cystic fibrosis

If a total bilirubin is 4.0 mg/dL and the conjugated bilirubin is 2.5 mg/dL, the unconjugated bilirubin is:

1.5 mg/dL.

3.0 mg/dL.

1.0 mg/dL.

2.0 mg/dL.

1.5 mg/dL

The cells that make up 70% of the liver's mass are:

None of the above.

Endothelial cells.

Hepatocytes.

Kupffer cells.

Hepatocytes

Which of the following is produced by the alpha cells of the islets of Langerhans in the pancreas?

Somatostatin

Glucagon

Gastrin

Insulin

Glucagon

Hydrochloric acid secretion is regulated by what hormone?

Cholecystokinin

Gastrin

Pepsin

Secretin

Gastrin

All of the following viral hepatitis transmitted by parenteral mode EXCEPT:

HBV.

HCV.

HDV.

HAV.

HAV (Hep A)

Which of the following tests is used to differentiate between pancreatic insufficiency and intestinal malabsorption?

Beta-carotene

D-xylose

Fecal fat analysis

Lactose tolerance test

D-xylose

List all Hepatitis illnesses that are related to parental transmission:

Hepatitis B, C, D

A patient result reflect of excessive levels of bilirubin in the blood, has a yellow tint to sclera. Their hepatic enzymes show no abnormalities. What stage of hepatic issue may the patient have?

Pre-hepatic

List all analytes within a Liver(Hepatic) Function Panel: List the 7

Total Bilirubin

Direct bilirubin

AST, ALP, ALT

Albumin

Total Protein

Within bilirubin metabolism— the degradation of RBC’s produces heme and bilirubin. Bilirubin is insoluble to water. What helps bilirubin transport by binding action?

Albumin

List the significant enzymes of the liver.

AST, ALT, ALP, 5’ Nucleotidase—- (GGT, LDH)

All are pre-hepatic disorders/causes of excess bilirubin except:

TR

Dubin-Johnson

Gilbert syndrome

HDN

Hemolytic Anemia

Dubin-Johnson

There are abnormally high levels of liver enzymes and the patient has gallbladder stones: what stage and probable issue?

a. pre-hepatic ; TR

b. post-hepatic ; obstructed bile

c. hepatic ; Hepatitis(inflamed hepatocytes)

a. post-hepatic ; obstructed bile

Hepatic disorder?

Crigler-Najjar