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What is neuroscience?
the scientific study of the nervous system
What is biopsychology?
the scientific study of the biology of behavior
When did biopsychology originate?
What publications lead to its creation?
20th century (end of the 19th)
"Origin of Behavior" (1949) by D. O. Hebb
What are the 6 subdivisions of biopsychology?
1. Neurophysiology - study of functions and activities of the nervous system
2. Neuropharmacology - study of the effects of drugs on neural activity
3. Neuropathology - study of nervous system disorders
4. Neurochemistry - study of the chemical bases of neural activity
5. Neuroendocrinology - study of interaction b/w the nervous system and the endocrine system
6. Neuroanatomy - study of the structure of the nervous system
What are some advantages and disadvantages of human vs non-human subjects?
1. Humans
- con follow instructions
- can report on subjective experience
- often cheaper
2. Non-humans
- brains & behaviours are simpler - more likely to reveal fundamental brain-behavior interactions
- you can use a comparative approach
- can do experiments considered unethical for humans
What are the 3 types of studies in biopsychology?
1. Experiments
2. Quasi-experimental studies
3. Case studies
What is the difference between pure and applied research?
Pure research is motivated by the curiosity of the researcher, purpose is to acquire knowledge.
Applied research is intended to bring some direct benefit to humankind
what is translational research?
aims to translate the findings of pure research into useful applications
What are the characteristics of research in physiological psychology?
subjects are almost always animals; usually pure research; usually surgical and electrical methods (i.e direct manipulation of the brain)
What are the characteristics of research in psychopharmacology?
most research is applies, used to develop therapeutic drugs; use lab animals and humans when ethical
What are the characteristics of research in neuropsychology?
study effects on brain damage on human subject; most are quasi-experimental studies; cerebral cortex is most likely to be damaged; most applied division; important basis in patient care and counselling
What are the characteristics of research in psychophysiology?
studies relation between physiological activity and psychological processes in humans; non-invasive recording procedure; usually use an EEG; also uses measures such as muscle tension, HR, BP, pupil dilation etc
What are the characteristics of research in cognitive neuroscience?
youngest division; most research involves humans, and is thus noninvasive; major method = functional brain imaging
What are the characteristics of research in comparative psychology?
deals w/ biology of behaviour; compare behaviour of different species to understand evolution, genetics, and adaptiveness; subfields include evolutionary psychology and behavioural genetics
What is the combined approach?
converging operations; made by using different approaches, each compensates for the short-comings of others
Explain the case of Jose and the bull.
Jose Deigado implanted an electrode into caudate nucleus; delivered an electrical stimulation when bull charged; this stoped the charge
his demo provided no support for his conclusion
Explain the case of Becky, Moniz, and prefrontal lobotomy.
Moniz's research was based on the observation of a single chimp in a single situation, there was a lack of appreciation of the diversity of the human brain
What is dichotomous thinking?
When did it originate?
rose following the dark ages in response to a 17th century conflict between since and the roman church;
Descartes argued that one part of the universe belonged to science and the other to the church;
said there were two elements to the universe:
1. physical matter
2. human soul
this is known as Cartesian Dualism
What are the two lines of evidence against Cartesian dualism?
1. Even the most complex psychological changes can be produced by damage or stimulation of the brain
2. nonhuman species (apes) posses some abilities that were once thought to be purely psychological and thus purely human
Why is nature vs nurture problematic?
it has been changed to "genetic factors vs learning"
genetic and experimental factors interact = interactionism
All behaviour is a product of what 3 factors?
1. organisms genetic endowment
2. expereince
3. perception of the current situation
What were the 3 types of evidence for Darwin's theory of evolution?
1. fossil records
2. structural similarities (homologous structures)
3. changes made by selective breeding (e.g. dog breeds)
What is the role of social dominance in evolution?
socially dominant males usually copulate more, therefore passing down more genes
socially dominant females are more likely to produce more and healthier offspring (more access to food and resources)
Summarize the course of human evolution.
450 million years ago - chordates
425 mya - vertebrates (bony fishes came first)
410 mya - first bony fishes left water
300 mya - reptiles
180 mya - mammals
160 mya- birds
6 mya - humans
What are the two advantages of bony fishes leaving the water?
1. could move from stagnant pools to nearby freshwater
2. could eat terrestrial food
What were the advantages to reptilian evolution?
shell covered eggs and dry scales meant they could live far from water - however this also reduced their resilience to water
what are 9 misunderstandings about evolution?
1. it is not a straight line
2. humans have no evolutionary supremacy
3. it is not always slow and gradual
4. very few products of evolution are around today (less than 1%)
5. evolution does no progress to preordained perfection
6. not are existing behaviours/structures are adaptive
7. not all existing adaptive characteristics evolved to perform their current function (exaptations)
8. similarities among species does not necessarily mean common origin
9. considerable evidence that homo sapiens mated with other species
What are the 3 major points about human brain evolution?
1. brain size has increased during evolution
2. most of the increase is in the cerebrum
3. increase in convolutions has greatly increased the SA of the cerebral cortex
Define polygyny and polyandry
polygyny = 1 male forms mating bonds with more than 1 female - this is b/c females make a far larger contribution to raising young, and therefore must be more selective in their mating partners.
polyandry = females form mating binds with more than 1 male - does not happen in mammals - e.g. seahorse
Explain monogamy
enduring mating bond b/w 1 male and 1 female
- 9% of mammals are monogamous
- occurs when females can raise more fit young offspring with undivided help from males
How can we predict mate bonding in humans through evolutionary theory?
1. men value youth and attractiveness (femininity); women value power and earning capacity
2. physical attractiveness best predicts which women will bond with men of high occupational status
3. men are more likely to commit adultery
What 4 factors lead to the rise of epigenetics?
1. genes constitute 1% of human DNA (junk DNA)
2. protein-encoding is a minor function of RNA
3. Mechanisms of gene-experience interactions unknown
4. new research techniques
what were 5 important discoveries of modern epigenetics?
1. non-gene DNA is still active (no longer junk)
2. multiple types of RNA found
3. Advances in understanding gene expression
- DNA methylation
- histone remodelling
4. RNA editing
5. Epigenetic mechanisms are enduring
- transgenerational epigenetics
What is ontogeny vs phylogeny?
ontogeny = development of individuals over their life span
phylogeny = evolutionary development throughout the ages
What were the main findings or the "maze-bright" vs "maze-dull" rat lab experiments?
that genetics play a role in behaviour
Explain phenylketonuria A
lack of phenylalanine hydroxylase; used to convert phenylalanine into tyrosine
- phenylalanine accumulates in the body
- low levels of dopamine due to lack of tyrosine
- results in abnormal brain developments
If infant is place on a phenylalanine-free diet, the effects are reduced
Explain how the development of birdsong demonstrates behavioural development.
birdsong develops in 2 stages:
1. sensory phase - several days after hatching
- form memories of adult song that guides the development of their own song
2. sensorimotor phase - when juvenile begins to tweet subsongs
- rambling vocalizations are usually refined
some species are age-ended while others are open ended learners
Remarkable features :
- lateralized to left hemisphere
- vocal centre is larger in males
- vocal centre doubles in size in spring
- growth of vocal centre is neurogenesis
What was the Minnesota Twin Study?
Adult monozygotic twins were much more similar in every aspect than adult dizygotic twins, regardless of if they were raised together or not
What is a heritability estimate?
numerical estimate of the proportion of
variability that occurred in a particular trait in a particular study as a result of the genetic variation in that study; how much to genes contribute to phenotypic differences
all complex traits have about 40-80 % heritability
What are the two main lines of twin studies?
1. Fraga and colleagues = took tissue samples of twins ranging from ages 3-74; screened DNA for methylation and histone modifications; found that young twins were epigenetically indistinguishable, but differences accumulate as they age; therefore monozygotic twins are NOT genetically identical
2. Wong and colleagues = DNA methylation is due to experiential factors; rates of methylation were the same in dizygotic and monozygotic twins
What did Turkheimer and colleagues find when they assessed the intelligence of twins from different socioeconomic statuses?
One can inherit potential for intelligence in an impoverished environment, but this potential is rarely realized (heritability drops to about 10%)
What 3 things must occur apart from cell multiplication for neurodevelopment?
1. cells must differentiate
2. cells must make their way to appropriate sites
3. cells must establish appropriate functional relations with other cells
define totipotent, pluripotent, multipotent, and unipotent
totipotent = cells has the ability to develop into any class of cell
pluripotent = developing cells that can develop into many, but not all, cell types
multipotent = new cells can develop into different cells of only 1 class (e.g blood cells)
unipotent = can only develop into one type of cell
What are the 5 phases of neurodevelopment?
1. induction of the neural plate
2. neural proliferation
3. migration and aggregation
4. axon growth and synapse formation
5. neuron death and synapse rearrangement
Describe the induction of the neural plate
- 3 weeks after conception, tissue destined to be the nervous system becomes the neural plate
- small patch of ectodermal tissue on the dorsal surface of developing embryo
- development of neural plate is induced by chemical signals from mesoderm
- after induction, lose some totipotentiality - become multipotent
- neural plate develops into neural groove - lips of neural groove fuse to from neural tube - neural tube defects can result from this process
- inside of neural tube eventually becomes the cerebral ventricles and spinal canal
- By 40 days, 3 swelling are visible at the anterior end - become the forebrain, midbrain, and spinal canal
Describe neural proliferation
once neural tube is formed, cells begin to proliferate (increase greatly in number)
does not occur simultaneously or equally across tube
most division is in the ventricular zone
controlled by chemical signals from 2 organizers:
1. floor plate - runs along midline of ventral surface
2. roof plate- runs along midline of dorsal surface
Describe migration
- cells still immature
- 2 types of migration:
1. radial migration - proceeds from ventricular zone in a straight line outward toward outer wall
2. tangential migration - occurs at a right angle to radial migration
- 2 methods of migration:
1. somal translocation - extension grows from developing cell in the direction of migration
2. glia-mediated migration - radial glial cells appear in developing neural tube
- providing a matrix for radial migration was assumed to be the only function of radial glial cells
- now we know many radial glial cells eventually develop into neurons
inside out pattern- each wave or cortical cells migrated through the already formed layer of the cortex
neural crest formed from cells that break off the neural tube - neural crest cells develop into neurons and gilal cells of the PNS
Describe aggregation
the process by which neurons align themselves
mediated by cell-adhesion molecules (CAMs)
- elimination of just one CAM is devastating for brain development
gap junctions are also involved
- bridged by connexins
Describe axon growth
at each growing tip of an axon or dendrite is a growth core - extends and retracts fingerlike structures called filopodia
Sperry suggested chemoaffinity hypothesis
Pioneer growth cones - first cones to travel along a particular route
Fasciculation = tendency of developing axons to grow along the paths established by preceding axons
Topographic-gradient hypothesis = axons growing from one topographic structure (e.g. retina) to another (e.g. optic tectum) are guided to specific targets that are arranged on the terminal surface in the same way as the axons' cell bodies are arranged on the original surface
- guided to their destination by 2 intersecting signal gradients
Describe synapse formation
once axons reach intended sites, they establish a synapse pattern - requires the coordinated activity of two neurons
synaptogenesis = formation of new synapses
- depends on presence of glial cells (astrocytes)
- ganglia w/ astrocytes formed 7x more synapses
formation occurs through signals from presynaptic and postsynaptic cells
chemical signalling important
Describe Neuron death
about 50% more neurons are produced than required
initially assumed to be a passive process (necrosis) but is now known to be active (apoptosis)
apoptosis is safer b/c necrosis involves the spillage of cellular contents into the ECM which can cause harmful inflammation
if apoptotic cell pathway is blocked - could result in cancer; if inappropriately activated - could result in neurodegenerative disease
two triggers for apoptosis:
1. some neurons are simply genetically programmed for early death
2. failure to obtain life-preserving chemicals
- grafting extra target structures to embryo before synaptogenesis reduces the death of neurons growing into the area
- destroying some neurons growing into an area before cell death increases the survival rate of remaining neurons
most prominent class of life-preserving chemicals are neurotrophins
- Nerve growth factor (NGF) = first neurotrophin to be isolated
Describe synapse rearrangement
when neurons die, the space they leave is filled by sprouting axons terminals of surviving neurons
thus, cell death results in massive rearrangement of synaptic connections
this process increases the selectivity of transmission
microglia play a role
Why does the human brain grow after birth?
1. synaptogenesis
- burst in visual and auditory cortexes in month 4 w/ max density at month 7 or 8
- much steadier rate in prefrontal cortex, max density at year 2
- greater plasticity
2. myelination of axons
- increases the speed of axonal conduction.
- sensory areas in first few months
- motor areas soon after
- prefrontal cortex continues into adulthood
3. increased branching of dendrites
- even mature dendrites can change their shape in seconds
NOTE: there are also significant regressive changes
What are the 4 functions of the prefrontal cortex?
What are preservative errors?
1. working memory - keeping relevant info accessible for short periods
2. planning and carrying out sequences of actions
3. inhibiting responses that are inappropriate in the current context but not others
4. following rules for social behavior
preservative errors made between 7-12 months but not after
preservation = tendency to continue making a formerly correct response when it is no longer correct
Define permissive experiences vs instructive experiences
permissive experiences = permit info in genetic programs of brain development to be expressed and maintained
instructive experiences = contribute to info in genetic programs and influence course of development
Define critical period vs sensitive period
critical period = when it is absolutely essential for an experience to occur w/in a particular interval to influence development
sensitive period = when an experience has a great effect w/in a particular interval but can still have weak effects outside the interval (most experiential effects)
Explain the effects of deprivation vs enrichment
deprivation (rats in the dark) - fewer synapses and dendritic spindles in visual cortexes - adults had deficits in vision (depth and pattern)
enrichment has beneficial effects - complex vs barren cages - thicker cortexes with more dendritic spines and more synapses
What did we learn from experiments of occular dominance?
depriving on eye of input for a few days early in life has lasting adverse effects - this does not happen is the other eye is also blindfolded
early monocular deprivation changes the pattern of synaptic input into layer IV of the visual cortex
widths of columns of input changes
Name 3 demonstrations of research for the effects of experience of topographic sensory cortex maps.
1. Roe and co. caused auditory complex to be organized retinotopically
2. Knudsen and Brainard; if visual world was shifted 23 degrees right, so was auditory map; objects heard where they were seen to be
3. early musical training expands auditory cortex for complex musical tones
Where does neurogenesis occur in adults?
What is the function of these new cells?
1. olfactory bulbs (not humans) and striatum
- created from adult neural stem cells in certain sites in the sub-ventricular zone of the lateral ventricles
- become interneurons
2. hippocampus
- can show substantial growth
- begins in dendrite gyrus
- becomes granule cells
- can be increased by exposure to enriched environment
unclear function, memory, pattern separation, mood & anxiety, adaptation to complex environments
What are 4 examples of experience reorganizing the adult brain?
1. Environmental enrichment
2. sensory and motor cortical maps
3. adaptation improved
4. brain damage
Explain Autism Spectrum Disorder
2 core symptoms:
1. reduced capacity for social interaction and communication
2. restricted and repetitive patterns of behaviour, interests or activities
75% male
may suffer from intellectual or learning disabilities
more likely to suffer from epilepsy
most prevalent neurodevelopment disorder
heterogeneous = impaired in some respects but superior in others
ASD savants have exceptional abilities in a certain area (10-30% of individuals with ASD)
genetic factors
potential neural mechanisms:
1. Associated with brain damage in the cerebellum, amygdala, and frontal cortex
2. abnormal reaction to faces associate with fusiform area
Explain Williams Syndrome
Intellectual disability with heterogenous pattern of ability and disability
1/7500 births
social, empathetic, talkative
language is remarkable for a low IQ
near perfect pitch
sense of rhythm
remarkable facial recognition
attentional problems
poor spatial ability
difficulty drawing objects
heart problems due to mutation of chromosome 7 (elastin)
thinning of cortex and white matter
- greatest in boundary of the parietal and occipital lobes and in orbitofrontal cortex
thicknening of the cortex in the superior temporal
gyrus, which includes primary and secondary auditory cortex
What are the major divisions of the nervous system?
central and peripheral nervous systems
CNS = brain and spinal cord
PNS = somatic and autonomic systems
SNS = interacts with external environment
ANS = regulates internal environment
(both have both afferent and efferent nerves)
ANS = parasympathetic and sympathetic nerves
what is the difference between afferent and efferent nerves?
in SNS - afferent nerves carry sensory signals from skin to brain; efferent nerves carry motor signals from CNS to muscles
in ANS - efferent nerves are sympathetic or parasympathetic
1. sympathetic nerves - motor nerves that project from CNS in lumbar and thoracic regions
2. parasympathetic nerves - motor nerves that project form brain and sacral region
What are some important distinctions between the sympathetic and parasympathetic nervous systems?
they are all two-stage neural pathways: they must synapse to other neurons to reach target
- parasympathetic neurons are much closer to their target organs (very short second-stage neurons)
sympathetic nerves stimulate, organize, and mobilize energy resources in threatening situations; parasympathetic act to conserve energy
each autonomic target organ receives opposing sympathetic and parasympathetic input, and its activity is thus controlled by relative levels of parasympathetic activity
sympathetic changes are indicative of psychological arousal, whereas parasympathetic changes are indicative of psychological relaxation
What are some important notes about the nerves of the PNS?
most project from spinal cord
12 pairs of exceptions (cranial nerves; project from brain)
includes purely sensory nerves such as olfactory (I) and optic nerves (III)
most contain both sensory and motor fibres
longest are vagus nerves (X)
disruptions of cranial nerves provide clues about location and extent of tumours
What are the 3 meninges? What is their purpose?
dura mater, fine arachnoid membrane, pia mater (adheres to surface of CNS)
encase brain and spinal cord for protection
Between fine arachnoid membrane and pia mater is subarachnoid space which contains large blood vessels and cerebrospinal fluid
What is the central canal?
small central channel that runs the length of the spinal cord
What are the cerebral ventricles?
4 large internal chambers of the brain: 2 lateral ventricles, the third, and the fourth
How does cerebrospinal fluid circulate?
subarachnoid space, central canal, and cerebral ventricles are all connected; a single reservoir
CSF cushions brain; people w/ fluid drained have raging headaches and stabbing pain
Where is CSF produced?
choroid plexus (network of capillaries) & excess CSF is continuously absorbed into large blood-filled spaces (dural sinuses) that run through dura mater & drain into jugular veins
What is hydrocephalus?
when the flow of CSF is blocked, for example by a tumour, causing walls of ventricles (& thus of entire brain) to expand
must drain excess fluid and remove obstruction
What is the blood brain barrier (BBB)?
it impedes the passage of toxic substances from blood to brain; the cells of blood vessels are tightly packed (unlike the rest of the body)
the degree to which therapeutic & recreational drugs work is based on the ease with which they cross the BBB
some large molecules (e.g. glucose) are actively transported across the BBB
many CNS disorders are associated with the impairment of the BBB
What is the neuron cell membrane?
lipid bilayer within which channel proteins and signal proteins are embedded
Name the 9 external structures of a neuron.
1. cell membrane
2. dendrites - short processes emanating from cell body that receive synaptic contact from other neurons
3. Axon hillock -cone shaped regions at the junction b/w axon and cell body
4. cell body - metabolic centre of the neuron (AKA soma)
5. Axon - long narrow process that extends from cell body
6. Myelin - fatty insulation around axons
7. Nodes of Ranvier - gaps b/w myelin
8. Buttons - buttonlike endings of axon branches, which release chemicals into synapses
9. synapses - gaps b/w adjacent neurons
Name the 9 internal structures of a neuron (7 in cell body, 2 in axon buttons)
1. Endoplasmic reticulum - system of folded membranes in cell body; RER plays a role in protein synthesis, SER plays a role in fat synthesis
2. Cytoplasm - clear internal fluid of cell
3. Ribosomes - proteins synthesis; located on ER
4. Golgi complex - packages molecules into vesicles
5. Nucleus - DNA - containing structure of cell body
6. Mitochondria - sites of aerobic energy release
7. Microtubules - responsible for the rapid transport of material throughout neurons
8. Synaptic vesicles - spherical membrane packages that store neurotransmitters
9. neurotransmitters - molecules that are related from active neurons and influence the activity of other cells
What are the 4 classes of neuron?
1. Multipolar neuron = more than 2 processes extending from cell body (most neurons)
2. unipolar neuron = one process extending from cell body
3. Bipolar neuron - two processes
4. interneuron - short (or no) axon, they serve to integrate neural activity w/in a single brain structure, not to conduct signals
What are the names of clusters of cell bodies in CNS and PNS?
What about bundles of axons?
CNS = nuclei; PNS = ganglia
CNS = tracts; PNS= nerves
What is the name of glia found in the CNS? What is its purpose?
What about in the PNS?
How are they different?
oligodendrocytes; extensions are rich in myelin and they form a myelin sheath
Schwann cells
each Schwann cell constitutes one myelin segment, each oligodendrocyte provides several myelin segments, often on more than 1 axon
Schwann cells can guide axonal regeneration (restricted to PNS)
What are microglia?
Class of glia that respond to injury or disease by multiplying, engulfing cellular debris or even entire cells, and triggering inflammatory response
smaller than other glial cells
What are astrocytes?
Largest glial cells; star-shaped
extensions cover the outer surfaces of blood vessels in the brain
play a role in the passage of chemicals from blood into CNS neurons & blocking other chemicals
How does a Golgi stain work?
potassium dichromate and silver nitrate react to form silver chromate; this invades neurons and stains them entirely black
How does the Nissl stain work?
use cresyl violet dye to bind to structures in neuron cell bodies; thus, you can estimate the amount of neurons in an area by counting dots
How does electron microscopy work?
coat thin slices of neural tissue w/ electron absorbing substance that is taken up by different parts of neurons to different degrees
then pass a beam of electrons through the tissue onto photographic film
a scanning electron micrograph captures images in 3D
What are the 2 types of neuroanatomical tracing techniques?
1. anterograde (forwards)
- used to trace paths of axons projecting away from cell bodies
- inject chemicals into the area
- after a few days, brain is removed & sliced, slices are treated to determine locations of the chemical
2. retrograde (backwards)
- trace paths of axons projecting into a particular area
- inject chemicals that are taken up by terminal buttons and transported backwards along axons to cell bodies
- brain sliced and treated
Explain the composition of the spinal cord
gray matter composed of cell bodies and unmyelinated interneurons
white matter is most myelinated axons
two dorsal arms of spinal gray matter = dorsal horn; two ventral arms = ventral horns
31 pairs of spinal nerves joined to cord via dorsal or ventral roots
- all dorsal root axons are sensory (afferent) unipolar neurons with cell bodies grouped together just outside cord to from dorsal root ganglia
What is the purpose of the myelencephalon?
AKA medulla
most posterior part of brain - composed largely of tracts carrying signals b/w brain and body
has a reticular formation
- complex network of ~100 tiny nuclei that occupy the central core of the brain stem
- named b/c of its netlike appearance
- involved in a variety of functions: sleep, attention, movement
What is the job of the metencephalon?
houses many ascending and descending tracts and part of the reticular formation
- these structures create a bulge = the pons
the other major division is the cerebellum
- important sensorimotor structure; damage makes it difficult to control movement
- however damage also causes other cognitive defect and so it therefore must have other purposes
What are the parts of the mesencephalon?
2 divisions:
1. Tectum (roof) = dorsal surface; in mammals composed to 2 pars of bumps, the colliculi
- posterior pair = inferior colliculi, auditory function
- anterior pair - superior colliculi, visual-motor function (directs body's orientation)
2. Tegmentum = ventral to tectum
- contains reticular formation, tracts of passage & 3 extra structures:
a) periaqueductal gray = gray matter situated around cerebral aqueduct (duct containing third and fourth ventricles); has a role in mediating analgesic effects of opioid drugs
b) substatia nigra
c) red nucleus; both b and c are important components of the sensorimotor system
What is the structure of the diencephalon?
1. Thalamus
- large, 2 lobed structure that constitutes the top of the brain stem
- one lobe on each side of the third ventricle - joined by massa intermedia
- most well-understood thalamic nulcei are sensory relay nuclei
- e.g. lateral geniculate nuclei (visual), medial geniculate nuclei (auditory), and ventral posterior nuclei (somatosensory system)
- most thalamic nuclei receive input from areas of the cortex and project it to other areas
2. Hypothalamus
- located just below anterior thalamus
- plays important role in motivated behaviour
- exerts effects by regulating release of hormones from the pituitary gland
- mammillary bodies are sometimes considered a part of the hypothalamus; they are a pair of spherical nuclei
What is the optic chiasm?
How is it formed?
the X-shaped structure formed at the point below the brain where the two optic nerves cross over each other.
some axons of optic nerves decussate (cross over to the other side of the brain) via optic chiasm
- decussating fibers (contralateral) vs nondecussating fibers (ipsilateral)
What is the telencephalon?
the largest division of the brain; where the most growth occurs
What is the cerebral cortex?
What is it made of?
outer layer of the cerebrum
small, unmyelinated neurons, therefore is gray and is sometimes called gray matter
- layer beneath the cortex is highly myelinated (white matter)
Why does the cerebral cortex have so many folds?
What are they called?
To increase the amount of cortex without increasing brain volume
- most mammals are lissencephatic (smooth brained) but most large mammals have convoluted cortexes
large furrows = fissures
small furrows = sulci
ridges b/w fissures and sulci = gyri
How are the cerebral hemispheres connected?
How are they divided?
a few tracts called cerebral commissures - largest is corpus callosum
longitudinal fissure (the largest fissure)
How are the four lobes of the brain separated? What are the four lobes?
what are the names of the large gyri that reside there?
central fissure and lateral fissure
frontal, parietal, temporal, occipital
precentral gyri (frontal), postcentral gyri (parietal), and superior temporal gyri (temporal lobe)
What is the functional area of the occipital lobe?
occipital cortex that analyzes visual input to guide behaviour
What is the functional area of the parietal lobe?
postcentral gyrus analyzes touch sensations; remaining cortex plays a role in perceiving locations of object and our bodies and then directing our attention
What is the functional area of the temporal lobe?
1. superior temporal gyrus - hearing and language
2. inferior temporal cortex - identifies visual patterns
3. medial portion of temporal cortex - memory