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Composed of the skin (largest organ of the body by weight)
integummentary system
the integummentary system as also know as the also known as the_______ membrane, and accessory structures (hair, nails, glands, receptors)
cutaneous
epidermis is what type of tissue cell
stratified squamous epithelium
epidermis lacks ____
blood cells
the deepest layer of epidermis is the ______ which is nourished by blood vessels in dermis
stratum basale
as cells grow in epidermis, they __________________, away from nutrient supply
migrate toward free surface
as cells in epidermis migrate towards free surface, older cells aka ___________, begin to flatten and die
keratinocytes
process of hardening, dehydration, and keratin accumulation that occurs in epidermal cells as they migrate outwards
Keratinization
Tough, fibrous, waterproof protein made and stored in cells
keratin
As cells reach outer surface, become tightly packed, develop desmosomes, form outermost layer-
stratum cornuem
In healthy skin, the production of epidermal cells is closely balanced with the
loss of skin cells
thickest skin is found on
palms and soles
most of the body has _____ epidermis
thin
funtions of epidermis- protect against ____ loss, harmful ______, mechanical ______, and _______
water loss, chemicals, injury, pathogens
extra credit question - favorite bone
sphenoid bone
Strata of the Epidermis (Big Sexy Girls Like Cake )
Basale, spinosum, granulosum, lucidum, corneum
deepest layer of epidermis. single row of cuboial or columnar cells
stratum basale
many layers of cells with centrally located, large, oval nuclei that become flattened as the move superficially from the developing keratin
stratum spinosum
3-5 layers of flattened granular cells containing fibers or keratin and shriveled nuclei
stratum granulosum
Found only in thick skin cells appear clear. The organelles and cel membranes are not visible
stratum lucidum
outermost layer. Many layers of flattened, keratinized, dead epithelial cells
stratum corneum
special cell in epidermis that is found in stratum spinosumm. Phagocytes; protect skin and underlying tissues from infections
Dendritic (Langerhans) Cells
Found in stratum basale, along with sensory nerve endings, for tactile discs in dermis, acts as sensory receptors for light touch
Tactile (Merkel) cells
specialized cell found in stratum basale, produce the pigment melanin, absorbs uv light from sunlight and provides skin color
Melanocytes
Skin color results mainly from
Melanin pigment
brownish-black bigment of epidermis
Eumelanin
reddish yellow pigment found in certain areas
Pheomelanin
increased blood in the area can cause pink/red blushing of skin. Lack of blood in area can cause bluish color from lack of oxygen in blood
hemoglobin
yellowing from build up of bilirubin. Seen in infants and people with liver failure
jaundice
Dermis is _____ than epidermis
thicker
the dermis contains projections called ____ between epidermal ridges
dermal papillae
the dermis binds epidermis to
underlying tissues
The dermis is a Connective tissue layer (mostly dense regular), containing ____ fibers, and ____ ____ processes
muscle, nerve cell
___________ Supply nutrients to all epidermal cells
dermal blood vessels
the dermis contains ____ ________, _______, and ________ glands
hair follicles, sweat, sebaceous
dermis contains sensory receptor for pressure called
Pancinian corpuscle
dermis contains sersory gland for light touch called
meissners corpuscles
what is the insulating layer beneath dermis
Subcutaneous layer/ Hypodermis
connective tissue found in hypodermis/ subcutaneous layer
areolar and adipose
the hypodermis/ subcutaneous layer is
not considered part of skin
3 parts of nail
Nail plate (body), nail bed, nail matrix
visible portion, keratinized cells, overlies nail beds
Nail plate (body)
surface of skin under nail plate
nail bed
active growth region, not visible, at proximal end of nail beds
nail matrix
tube like depression of epidermal cells from which hair develops; extends into dermis or the subcutaneous layer
hair follicle
attached to hair follicle, contracts in response to cold or fear, causes goosebumps
arrector pili
Most numberous sweat gland, consists mainly of water, some salts, wastes
Eccrine
eccrine responds to
increased body temp
eccrine glands are open to body surface _____ _____-
through pores
Gland in axillary and and groin areas; open into hair follicles
apocrine glands
apocrine glands respond to
emotions, pain, pheromones
ceruminous glands
ears
mammary glands
milk
functions of skin (PB, S, E, PVD, RBT)
protective barrier, sensation , excretion, production of vitamin D, regulation of body temperature
primary method of heat loss through skin, infrared heat rays travel from warmer skin the cooler environment
radiation
method of heat loss through skin, heat moves from warmer skin to cooler objects it is in contact with
conduction
method of heat loss thru skin, Heat loss from skin into circulating air currents
convection
method of heat loss thru skin, Heat is lost through sweat as it evaporates, and carries heat away from the skin
evaporation
thermorecepters signal hypothalamus, Vasodilation of dermal blood vessels, Vasoconstriction of deep blood vessels, Sweat glands are activated. this is a reaction to an increase or decrease in body temp
increase
Thermoreceptors signal hypothalamus, Vasoconstriction of dermal blood vessels, Vasodilation of deep blood vessels, Sweat glands are inactive, Muscles contract involuntarily (shivering). reaction to an increase or decrease in body temp
decrease
normal response to injury or stress, attempt to restrict spread of infection
inflammation of skin
blood vessels in affected tissues dilate and become more permeable, allowing fluids to leak into the damaged tissues
inflammation
Inflammed skin may become: (R,S,W,P)
red, swollen, warm, painful
only affects epidermis, results in epidermal cells along its margin dividing more rapidly than usual, to fill gap
shallow cut
reaching dermis or subcutaneous layer, results in blood vessels breaking; released blood forms a clot:
deep cut
after a deep cut, blood will form clot which consists of
fibrin, blood cells, platelets
clot and dried tissue fluid from
scab
after a cut and scab formation, epithelial cells will reproduce and
fill the wound
during deep wound healing process, _______ secrete collagen fibers to bind wound together
fibroblasts
during wound healing, growth factors stimulate ____ ______ _______
new tissue formation
during wound healing, _______ cells remove dead cells and debris, scab sloughs off
phagocytic
during wound healing, excess collagenous fibers may form elevated mass called
scar
superficial, partial thickness burn, injures only epidermis
1st degree
1st deg burn heals in days-to weeks, no scarring, examples include
sunburns and minor burns
deep, partial thickness, destroys epidermis and some dermis, may blister, stem cells in hair follicles help to regenerate , usually no scarring
2nd degree
examples and 2nd degree burn
severe sunburns and hot water
full thickness burn, destroys dermis, epidermis, and accessory structures, requires skin graft
3rd degree
skin burn severity is measured by the
rule of 9s
the rule of 9s estimates the severity of skin burns and figures
plans for hydration and skin
during aging, epidermis becomes _____, loss of _____ leaving person feeling ___
thinner, fat, cold
wrinkling, sagging of skin occur due to
decreased collagen and elastin
bones in the arm, (Humerus, radius, ulna) and leg (femur, tibia, fibula).
long bones
wrist and ankle bones, cube like, include sesamoid bones, which are embedded in tendons
short
ex- skull bones, plate like
Flat bones
Vertebrate is example of what type of bone?
Irregular
Provide shape, protect, aid movement , produce blood cells, store inorganic salts. These are all functions of what?
Bones
Part of long bone: expanded end
Epiphysis
Part of long bone: bone shaft
Diaphysis
Part of long bone:between diaphysis and epiphysis, widening part
Metaphysis
Part of long bone: covers epiphysis
articular cartilage
Part of long bone: encloses bone; dense connective tissue
Periosteum
Part of long bone: hollow chamber in diaphysis; contains marrow
Medullary cavity
Part of long bone: lines spaces, cavity
Endosteum
Part of long bone: Red or yellow marrow, lines medullary cavity, spongy bone spaces
Bone marrow
Nature bone cells
Osteocytes
Make bones
Osteoblasts
Break down bone
Osteoclasts
cylindrical units called osteons. Osteons and layers of matrix, lamellae, cluster around central canal in each osteon. What type of bone is this
Compact
Strong and solid, Weight-bearing, Resists compression
Compact bone
branching plates called trabeculae, Somewhat flexible, spaces between trabeculae that reduce the bone’s weight
Spongey bone