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biological macromolecule
large, complex substituted organic molecules with specific roles in organisms
monomers
single unit building blocks of larger molecules
polymers
long chain of monomers, large molecules; Four Major Groups: Carbohydrates, Proteins, Lipids, Nucleic Acids
carbohydrates
composed of carbon, hydrogen, and oxygen; used primarily as source of energy in cellular respiration; some carbohydrates function as structural compounds
monosaccharides
simplest carbohydrates, monomers; single-ringed; also called sugars; names end in –ose
isomers
two molecules that share the same molecular formula but different structural formulas
disaccharides
double-ringed sugar; form through dehydration synthesis
dehydration synthesis
formation of a bond between monomers caused by the removal of water
hydrolysis
breaking of a bond between monomers by adding water
polysaccharides
complex carbohydrates/polymers; made up of chains of monosaccharides
starch
molecule in which plants store excess sugar in roots, stems, and leaves; easily digested
cellulose
tough, structural polysaccharide found in plant cell walls; cannot be digested
glycogen
molecules used by animals to store excess sugar in the liver (4-6 hr supply). Animal starch, highly branched
chitin
tough structural polysaccharide found in the exoskeleton of insects, spiders, and crustaceans
proteins
contain C,H,O,N,S
- found in hair, nails, skin, muscle, and feathers (structure)
- perform functions: hormones, antibodies, and enzymes
Amino Acids
- monomers of proteins
- 20 different types
Polypeptides
- polymers; long chains of amino acids
- range in size from 50 amino acids to 100,000 amino acids
Protein
One or more polypeptides folded into specific shape
Enzymes
- Organic catalysts
- names end in –ase; Lipase, Catalase, Amylase
- react only with a substrate that matches its unique 3D shape
Catalyst
a substance that speeds up chemical reactions without being changed/destroyed itself
Substrate
the specific substance(s) undergoing a chemical reaction enzyme temporarily bonds to the substrate(s)
Denaturation
- destruction of the normal shape of the protein, no longer matches shape of the substrate
- caused by changes in pH and high temperature
Activation Energy
Energy needed to start a chemical reaction
Lipids
- contain carbon, hydrogen, and oxygen
- insoluble in water (hydrophobic/non-polar)
- reserve energy in animals
- includes triglycerides (fats and oils), waxes,
and steroids
Triglycerides
large lipid polymers found in fat/oils
made of fatty acids and glycerol
Phospholipid
- special type of triglyceride found within cell membranes
- both polar and nonpolar
Nucleic Acids
Contain the code which stores hereditary information
Nucleotide
monomer; composed of: 1. 5 carbon sugar
2. Phosphate group
3. Nitrogen Base
DNA Nucleotide
a. Contains deoxyribose sugar
b. Possible bases:
- thymine
- guanine
- cytosine
- adenine
RNA Nucleotide:
a. Contains ribose sugar
b. Possible bases:
- uracil
- guanine
- cytosine
- adenine
DNA Function
a. Copied during cell division
b. Found only in the nucleus
c. Stores the genetic code; determines protein structure
RNA Function
a. Temporary copy of genetic code
b. Found in nucleus, ribosome, cytoplasm of the cell
c. Directly used in protein synthesis
Prokaryotic Cells
- simplest, most ancient/oldest types of cell
- found only in bacteria; no nucleus and no membrane bound organelles.
Eukaryotic Cells
- more modern, complex cells
- contain nucleus and “membrane-bound” organelles
- found in plants, animals, fungi, protists
Cell Membrane
Outer boundary of the cell; separates the cell from the external environment
Regulates what goes in or out of cell
Cytosol
Clear fluid filling the cell in which organelles are suspended
Nucleus
contains the genetic material; controls the activities of the cell
Surrounded by nuclear membrane
Nucleolus
Found within nucleus, site where ribosomes are made
Endoplasmic Reticulum
“intracellular highway”; system of transport tubules within the cell
Ribosomes
Location where proteins are assembled; most numerous organelle
Mitochondria
“Powerhouse” of the cell; location where ATP is made by aerobic respiration
Lysosome
Contain digestive enzymes, break down foods and worn out cell parts
Peroxisome
Small, membrane bound, contain toxic peroxides that are safely broken down
Cytoskeleton
Provides shape and support for the cell
Vacuole
Storage organelles, stores materials and wastes
Centrioles
Aid in cell division
Cell Walls
Found outside cell membrane, made of cellulose; provides support
Chloroplasts
Contain chlorophyll; site of photosynthesis
Chromoplasts
Contain accessory pigments that aid in photosynthesis
Leukoplasts
Store starch
DNA replication
DNA making a copy of itself prior to cell division
G1 Stage
Cell volume increases; cell differentiation/growth completed; cell begins to function
G0 Stage
Stage outside the cell cycle in which cells do not copy their DNA and do not prepare to divide; many cells, such as mature nervous cells in the human body, are in this stage; may last weeks or indefinitely
S Stage
DNA Replication occurs; all cell activity ceases as replication is completed; the onset of the S Stage is triggered by a buildup of the hormone “S-Cyclin”
G2 Stage
Cell function resumes; cell increases in volume as all cell contents double in preparation for cell division