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what is the recommended secondary prevention goal with high risk ASCVD patients?
LDL-C <55 mg/dL, non-HDL-C <85 mg/dL
what is the recommended statin intensity in patients with clinical ASCVD?
high intensity or maximally tolerated statin
what is the general sequence of drugs for treating dyslipidemia?
statin (MAXIMIZE FIRST BEFORE MOVING TO PROCEEDING OPTIONS)
ezetimibe
PCSK9 mAb (alternative—> inclisiran)
bempedoic acid
what is the suggested Clinical ASCVD goal for patients who are NOT at high risk?
LDL-C < 70 mg/dL, non-HDL-C <100 mg/dL
what is the recommended statin intensity in patients without clinical ASCVD?
high intensity or max tolerated statin (rosuvastatin 20-40mg OR atorvastatin 40-80mg)
what defines clinical ASCVD secondary prevention patients?
patients who have either:
experienced two or more ASCVD events OR
experienced 1 ASCVD event + two or more high risk conditions