Non- Competitive inhibitors.

https://www.youtube.com/watch?v=N6aumZOIMU4

Where do non competitive inhibitors bind to

A different site on the enzyme molecule. this is called the allosteric site.

What happens when non comp inhibitors bind to allosteric site

It causes the tertiary structure of the enzyme to change, this means shape of the active site changes, so its no longer complementary to the substrate.

What happens if concentration of substrate concentration increases,

The non competitor inhibitor reduces rate of reaction by same amount, this is because non comp inhibitor changes shape of active site, so if concentration of substrate increases, it still cannot successfully bind with a

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