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What receptor type is the fastest?
Ligand-gated ion (ionotropic)
What are the four receptor superfamilies?
ligand gated ion channels
G protein coupled receptors
Kinase-gated receptors
nuclear receptors
What is an example of a ligand gated receptor?
nicotinic and ACh receptors
What is an example of a G-protein coupled receptor?
muscarinic and ACh receptors
What is an example of a kinase-linked receptor?
cytokine receptors
What is an example of a nuclear receptor?
oestrogen receptor
How do nicotinic ACh receptors work?
It has two alpha subunits and one requires ACH to bind to open the channel
What does Gs do?
stimulated adenylyl cyclase and activates Ca2+ channels
What does Gi do?
inhibits adenylyl cyclase and activates K+ channels
What does Gq do?
activates phospholipase C
Wat does Go do?
inhibits Ca2+ currents
What does Gt do?
stimulates adenylyl cyclase in the eye
What does Gdf do?
stimulates adenylyl cyclase in the nose