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Epineurium
Connective tissue layer surrounding entire nerve
Perineurium
Connective tissue layer surrounding a fascicle (bundle of axons)
Endoneurium
Connective tissue layer surrounding individual axon
Fascicle
Bundle of nerve fibers within a nerve
Dura mater
Outer tough meningeal layer protecting brain and spinal cord
Arachnoid mater
Middle web-like meningeal layer
Pia mater
Inner delicate meningeal layer attached to brain surface
Central canal
CSF-filled channel at center of spinal cord
Posterior gray horn
Region of spinal cord gray matter containing sensory neuron processing
Anterior gray horn
Region of spinal cord gray matter containing motor neuron cell bodies
Lateral gray horn
Region containing autonomic neurons (thoracic/lumbar only)
Gray commissure
Connects left and right sides of spinal cord gray matter
Dorsal column pathway
Carries fine touch, vibration, proprioception; crosses in medulla
Spinothalamic pathway
Carries pain, temperature, crude touch; crosses in spinal cord
Spinocerebellar pathway
Carries subconscious proprioception to cerebellum; does not cross
Dorsal root ganglion
Contains sensory neuron cell bodies entering spinal cord
Ventral root
Contains motor neuron axons leaving spinal cord
Phrenic nerve
Innervates diaphragm; arises from C3–C5
Monosynaptic reflex
Reflex involving only sensory and motor neuron (example: patellar reflex)
Polysynaptic reflex
Reflex involving interneurons (example: withdrawal reflex)
Choroid plexus
Structure that produces cerebrospinal fluid
CSF functions
Cushions brain, removes waste, transports nutrients, stabilizes environment
Cerebrum
Responsible for conscious thought, voluntary movement, memory, sensation
Cerebellum
Coordinates movement, posture, balance, motor learning
Thalamus
Major sensory relay station to cerebral cortex
Hypothalamus
Maintains homeostasis and controls pituitary gland
Brainstem
Includes midbrain, pons, medulla; controls vital functions
Pons
Regulates breathing rhythm and sleep
Medulla oblongata
Controls heart rate, breathing, blood pressure
Limbic system
Controls emotion, behavior, memory
Hippocampus
Important for memory formation
Reticular activating system
Controls alertness and consciousness
Corpus callosum
Connects left and right cerebral hemispheres
Central sulcus
Separates frontal and parietal lobes
Longitudinal fissure
Separates left and right cerebral hemispheres
Primary motor cortex
Controls voluntary skeletal muscle movement
Primary somatosensory cortex
Receives touch sensation
Visual cortex
Processes vision in occipital lobe
Auditory cortex
Processes sound in temporal lobe
Association areas
Integrate and interpret sensory information
Basal nuclei
Help regulate movement coordination
Frontal lobe
Responsible for planning, movement, personality
Parietal lobe
Processes somatic sensory information
Temporal lobe
Processes hearing and memory
Occipital lobe
Processes vision
Alpha waves
Brain waves during relaxed wakefulness
Beta waves
Brain waves during alert mental activity
Theta waves
Brain waves during light sleep
Delta waves
Brain waves during deep sleep
Otolith
Calcium crystals detecting gravity and linear movement
Otic
Relating to the ear
Optic
Relating to the eye or vision
Myopia
Nearsightedness; image forms in front of retina
Hyperopia
Farsightedness; image forms behind retina
Keratotomy
Surgical reshaping of cornea to correct vision
Lacrimal glands
Produce tears
Tympanic membrane
Eardrum; vibrates with sound waves
Oval window
Membrane receiving vibrations from stapes into cochlea
Round window
Relieves pressure within cochlea
Vestibular system
Responsible for balance and equilibrium
Olfactory receptors
Modified bipolar neurons detecting smell in olfactory epithelium
Olfactory pathway
Receptors → olfactory nerve → olfactory bulb → olfactory cortex
Olfactory receptor replacement
Regenerated about every 30–60 days
Nasal conchae function
Warm, humidify, and filter air; enhance smell detection
Animals stronger smell reason
Larger olfactory epithelium and more receptors
Smell interpretation
Brain recognizes odor based on receptor activation patterns
Taste receptors location
Located within taste buds
Taste bud receptor count
Each taste bud contains about 50–100 receptor cells
Taste receptor replacement rate
Replaced about every 10 days
Fungiform papillae
Taste papillae located mostly on anterior tongue
Circumvallate papillae
Large papillae located at posterior tongue
Foliate papillae
Papillae located along sides of tongue
Filiform papillae
Papillae lacking taste buds; provide texture
Five taste sensations
Sweet, sour, salty, bitter, umami
Gustducin
G-protein used in sweet, bitter, umami taste detection
Salt and sour detection
Detected via direct ion channels
Sweet bitter umami detection
Detected via G-protein-coupled receptors
Percent taste dependent on smell
Approximately 80 percent
Accessory eye structures
Include lacrimal glands and rectus muscles
Three tunics of eye
Fibrous, vascular, neural layers
Fibrous tunic
Includes sclera and cornea
Vascular tunic
Includes choroid, iris, ciliary body
Neural tunic
Includes retina
Rods
Detect dim light; provide night vision
Cones
Detect color and sharp detail
Cataract
Clouding of the lens causing blurred vision
Parasympathetic pupil constriction nerve
Oculomotor nerve (CN III)
Hair cells stimulation surface
Hair cells contact tectorial membrane
Sound transmission pathway
Ear canal → tympanic membrane → ossicles → oval window → cochlea → hair cells → CN VIII
Auditory ossicles
Malleus, incus, stapes
Stapes function
Presses on oval window transmitting vibration to cochlea
Vestibule
Detects head position relative to gravity
Semicircular canals
Detect rotational movement of head
Otolith function
Detect linear acceleration and gravity
Endocrine glands
Release hormones directly into bloodstream
Peptide hormones
Derived from amino acids; bind membrane receptors; use second messengers
Steroid hormones
Derived from cholesterol; bind intracellular receptors; alter gene expression
Amino acid derivative hormones
Include epinephrine, norepinephrine, thyroid hormones, melatonin
First messenger
Hormone outside target cell
Second messenger
Intracellular signal molecule such as cAMP