section 6: Key Concepts and Timelines
Call Kai
Learn
Practice Test
Spaced Repetition
Match
Flashcards
Knowt Play1/4
There's no tags or description
Looks like no tags are added yet.
Name | Mastery | Learn | Test | Matching | Spaced | Call with Kai |
|---|
No analytics yet
Send a link to your students to track their progress
5 Terms
What is the fundamental "beads on a string" structure of chromatin composed of?
Nucleosomes, which consist of DNA wrapped around histone proteins.
What is the primary function of chromatin remodelers in relation to nucleosomes?
To use ATP to slide, evict, or restructure nucleosomes, thereby regulating access to DNA.
What are the key roles of the BAF (SWI/SNF) complex in controlling transcription?
It creates accessible chromatin at promoters and enhancers, facilitating transcription factor binding and evicting repressors to activate gene expression.
What is the historical progression of understanding the BAF complex?
It started with the discovery of SNF genes in yeast (1981), moved to linking them to chromatin structure (1992), demonstrated nucleosome sliding (1999), and culminated in understanding its role in human cancer and developmental syndromes