Cancer Immune Surveillance and Immunotherapy

Flashcards covering key concepts in cancer immune surveillance and immunotherapy.

Cancer Immunology

Study of how cancer interacts with the immune system.

Immune Cancer Surveillance

The process by which the immune system monitors and identifies cancerous cells.

Tumour-associated Antigens (TAA)

Antigens that are expressed on tumor cells and can trigger an immune response.

The 'Three E’s' of Cancer Immunity

Elimination, Equilibrium, Escape; the stages of cancer immune response.

Immunostimulatory Cytokines

Cytokines that enhance the immune response against cancer.

Coley's Hypothesis

The theory that infections can induce cancer regression through an immune response.

Monoclonal Antibodies

Antibodies made by identical immune cells that are clones of a unique parent cell, used in cancer treatment.

Antibody-drug Conjugates (ADCs)

Therapies that link an antibody to a chemotherapy drug for targeted cancer treatment.

Graft versus Cancer Effect

The phenomenon where donor immune cells attack the recipient's cancer cells.

Cytokine Proteins

Signaling molecules of the immune system that regulate immunity.

Dendritic Cell Cancer Vaccines

Vaccines made by loading tumor antigens into dendritic cells to elicit an immune response.

Chimeric Antigen Receptor T-cells (CAR-T cells)

T-cells engineered to express a receptor specific for tumor antigens.