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T/F In healthy patients, the effects of most anesthetic agents on the GIT are usually short-lived and normal function returns with the decline of drug levels But patients with GIT disease may have prolonged abnormal functions
change in saliva production
vomiting
ileus
regurgitation
gastroesophageal reflux
constipation
reduced secretion of digestive fluids
aerophagia (associated with panting)
what are some possible GI effects of anesthetic agents? (8)
dehydration
hypovolemia
hypotension
What fluid status abnormalities can occur in patients with GIT disease that may affect the overall stability of the patient? (3)
chill
Patients with GIT diseases may have anemia, protein loss, electrolytes abnormalities, acid-base derangements, hyoxemia, myocardial dysfunction, and vomiting and aspiration that may affect the overall stability of the patient
chill?
vomiting
what is a common side effect of many anesthetic drugs because blood born substances can stimulate the chemoreceptor trigger zone (CRTZ) and the neural pathway can activate the vomiting center (VC)?
true
T/F the vomiting center can be stimulated by the CRTZ, histamine, acetylcholine, dopamine, serotonin, neurokinin-I, opioids, and a2 agonists
hyperproteinemia
anemia
what are two systemic conditions that are associated with GIT disease that are pre anesthetic considerations with endoscopy of the upper or lower GIT?
opioids
a2 agonists
what two drug classes may constrict GIT sphincters and therefore, make passing endoscopes difficult so should be avoided for GIT endoscopy?
what drug should be used to sedate these patients instead?
hypotension
hypoventilation
vagal response
puts pressure on diaphragm (which puts pressure on lungs -> hypoventilation)
what can happen when the GIT is over inflated during endoscopy? Why?
gagging
swallowing
regurgitation
The patient should be in an appropriate plane of anesthesia for endoscopy, what are signs that they are not at an appropriate plane? (3)
emergency situations
GDV
intestinal obstruction
hemo-abdomen
neoplasia
septic peritonitis
biopsy
patients undergoing anesthesia for exploratory laparotomy are some of the most unstable patients. What are some examples of indications for exploratory laparotomy? (7)
patient stabilization
fluids!!!
gastric decompression
blood transfusion
antimicrobial therapy
pain management
what is key to successful anesthesia for exploratory laparotomy?
how can this be achieved? (5)
volume replacement
electrolyte therapy
acid-base normalization
what are some things fluids can be used for? (3)
hypoproteinemia
you should be cautious with fluid therapy in patients that have what abnormality?
hypotension
arrhythmias
hypoventilation
what complications should you be prepared for/expect during an exploratory laparotomy? (3)
opioids
the anesthetic protocol for exploratory laparotomy patients should be built around what class of drugs?
MAC reduction
analgesia
minimal effects on cardiovascular system
Why should the anesthetic protocol for exploratory laparotomy patients be built around opioids? What are the benefits? (3)
cardiovascular
a2 agonists
acepromazine
you should minimize dosages of drugs that have large effects on the ___________ system when developing an anesthetic protocol for exploratory laparotomy patients
what are two drugs you should minimize dosages of in these patients?
premedication: opioid
induction: propofol or alfaxalone or opioid/benzodiazepine
maintenance: inhalants or opioid infusion, or lidocaine infusion (+/-)
opioid/benzodiazepine (very unstable patients)
what is the typical anesthetic protocol for exploratory laparotomy patients? premedication (1), induction agents (2), and maintenance drugs (3)
which induction agents should be used in very unstable patients?
lidocaine
what sodium channel blocker is the only local anesthetic that can be given IV, is anti reperfusion injury, MAC reducing, and helps treat arrhythmias (VPCs)?
VPC
what is the most common arrhythmia in abdominal patients?
crystalloid fluids
blood pressure support
what adjunctive therapies should be considered for exploratory laparotomy patients? (2)
Dopamine
norepinephrine
vasopressin
dobutamine
phenylephrine
what are some drugs that could be used for blood pressure support? (5)
Alpha
vascular tone
beta
contractility
Dopamine primarily works on (choose one: alpha/beta) receptors to improve (choose one: vascular tone/contractility)
while dobutamine primarily works on (choose one: alpha/beta) receptors to improve (choose one: vascular tone/contractility)
False, it is extensive and intensive
T/F anesthesia monitoring for exploratory laparotomy patients is pretty chill
ECG
blood pressure
ETCO2
SPO2
arterial blood gas and electrolyte analysis
what monitoring tools should be used to monitor anesthesia in exploratory laparotomy patients? (5)
VPCs
V-tach
what two arrhythmias are we most concerned about with exploratory laparotomy patients?
Direct
a (choose one: direct/indirect) blood pressure should be used in very unstable patients
true
T/F exploratory laparotomy patients frequently require assisted ventilation
hypoxemia
what are we monitoring for with SPO2?
true
T/F arterial blood gas and electrolyte analysis may be necessary for ongoing therapeutic decisions