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reproductive physiology
the study of the mechanical, physical, and biochemical functions of the reproductive system
andrology
branch of repro phys that deals with the study and treatment of maile animals and humans
gynecology
deals with repro issues in women
Theriogenology
The branch of veterinary medicine concerned with reproduction in animals
obstetrics
branch of repro physiology, vet medicine, and human medicine that specializes in the female before, during, and after pregnancy
Aristotle
-proposed fetus originated from menstrual blood since menstruation did not occur during pregnancy
-thought seminal fluid arose from all parts of the body and the testes were pendular weights that kept the transport ducts from getting kinked or coiled
Fallopius
fallopian tubes
-described oviducts
Coiter (1573)
corpus luteum
Regnier de Graaf
described antral follicles
-rabbits
-# of scars on ovary = amount of young
- wrong idea that the entire follicle was the egg
Van Leeuwenhoek
-observed semen and discovered that moving particles as "animalcules"
-developed simple microscope
Spallanzani
preformed 1st AI in dogs
dumas
discovered follicles containted ova
-concluded that "animalcules" now called spermatozoa were responsible uniting with the ova to produce an embryo
modern
gonads makes steroid hormones
cycle
puberty, copulation, pregnancy, parturition and lactation, repeated, then repro senescence
major structures of female repro tract
ovaries, oviduct, uterus, cervix, vagina, external genitalia
female repro tract lies
directly beneath the rectum
what seperates the female tract from the rectum
rectogential pouch
what is the purpose of the retogenital pouch
allows if manual palpation or ultrasonic examiniation
-ovarian staus
-pregnancy
-AI
-identify abnormalities
What tracts are too small or palpation per rectum
ewe, sow, bitch, and qween
palpation of the uterine artery
arterial tone and fremitis
what are the series of interconnnected tubes
tubular components
-oviducts, uterus, cervix, and vagina
what are the four distinct concentirc layers of the female repro tract
serosa, muscularis, submucosa, and mucosa
serosa
a single layer of squamous cells that cover the outer surface of the tract
muscularis
double layer of smooth muscle
-outer longitudinal layer and inner circular layer
-provides the ability to contract
the muscularis provides the ability to contact which allows for
transportation of secretory products, gametes, embroys, and explusion of the fetus and membrane
submucosa
layer of varying thickness
-houses
-supports tissue for mucosal layer
mucosa
secretory layer of epithelium
Each part of the tract is lined with what?
different types of epithelium
mucosa has
different functions in different region
oviduct
ciliated and non-ciliated columnar
what does the oviduct provide
fliud and movement of material along the oviduct
Posterior vagina
stratified (multiple) squamous
what does the posterior vagina provide
protection during copulation
the mucosa develops in the
rectroperitoneal position
peritomeum
membrane that lines the abdomial cavity `
the peritomeum completely
surrounds and covers the tract
The tract grows and pushes against
the peritoneum
As the tract grows
it becomes completely surrounded the the peritoneum
Peritoneum eventually fuses to form
a double layerd CT sheet that supports and suspends the tract
what is the suspensorty tissue called
broad ligament
the broad ligament houses
The vascular supply, nerves, and lymphatic drainage of the tract
what are the components of the broad ligament
mesovarium, mesosalpinx, mesometrium
mesovarium
cranial portion that supports the ovary
the mesovarium forms the
hilus of the ovary
What is the pupose of the utero-ovarian ligament
-additonal support ligament
-attaches the ovary to the uterus
is the utero-ovarian ligament actually part of the broad ligament
no
mesosalpinx
thin portion of the board ligament that supports the oviduct
what else does the mesosalpinx form
a pouch that surrounds the ovary
-helps orient the infundibulum so ova released have a high chance of getting into the ovary
-helps eggs not leave the ovary
mesometrium
largest part of the broad ligament
-supports the uterine horns and body of the uterus
dorsal portion of the mesometrium is
continuous with the dorsal peritoneum and this the uterus litrelly hangs from the dorsal body walls
RGP
rectum genital pouch
Ovary
structure on the ovary undergo constant change
-dramatic and predictable
-follicles, estrogen production, ovulation, CL, progesterone production, lysis of CL
Sturcture of ovary
ovoid, dense structure
primary fucntion of ovary
produces females gametes and hormones
tunica albuginea
outer surface
- CT
- single layer of cuboidal cells called germinal epithelium
ovarian cortex
directly beneath the tunica albuginea
-houses the oocytes and follicles
the ovarian cortex is the site of formation of the
CH- corpus hemorrhagicum
CL- corpus lutum
CA- corpus albicans
corpus hemorrhagicum
protrusion of tissue and ruptured blood vessels following ovulation
-"bloody body"
corpus luteum
large structure that produces progesterone (P4)
-"yellow body"
corpus albicans
white, scar-like structure, CL in degeneration
-connective tissue replacing secretory tissue
ovarian medulla
Central part of the ovary.
Houses vasculature, nerves and lymphatics.
Dense connective tissue.
Mare
medulla and cortex are reveresed
ovulation occues at one location
folliciles can be palpayed per rectum, but not CL
AF
antral follicle
UOL
uteris ovarian ligament
ovaries can be distingished tactiley in some species using
palpation per rectum
determine fucntional stauts
follicles or CL
ovarian structure can be seen with
ultrasound as well as palpation per rectum
folliculogenesis
The process of follicle development and maturation
various types of follicles represents different
stages of development and maturity
what are the four types of follicles
Primordial, Primary ,Secondary ,Tertiary
Primordial follicles
microscopic, most immature, smallest
oocyte surrounded by a single layer of squamous cells
primary follicles
oocytes surrounding by a single layer of cuboidal cells, or folliculair cells
-females are born with a life time supply of primordial and primary follicles
primary follicles do not
divide, mature or degenerate
seconary follicles
microscopic
two or more layers of follicular cells
2 layes of cuboidal cells
secondary follicles are characterized by
being surrounded by a relatively thick translucent layer called zona pellucida
Tertiary or Antral follicle
characterized by fluid filled cavity called antrum
-fluid is called follicular fluid
When the tertiary follicle becomes a dominant preovulatory follicle is is called
Grannfian follicle
what are the three layers of the antra follicles
theca externa, theca interna, granulosal cell layer
Theca externa
loose connective tissue that surrounds and supports the follicle
theca interna
beneath the externa
-responsible for the production of the androgens under the influence of luteinizing hormone LH
granulosa cells
membrana granulosa
-makes a variety of material and have follicle stimulation hormmones
the granulosa cells contain
estogen
inhibin
follicular fliud
granulosa cells are belived to
govern the maturation of the oocytes
ovulation
small blood vessle rupture causing local hemorrhages
loss of fliud from the antrum causes
follicles to collapse into many fold
CH forms what two cells types
theca internal and granulosa cells
CL produces
progesterone anf essentials for maintenance of pregnancy
what are the three parts of the oviduct?
infundibulum, ampulla, isthmus
infundibulum
terminal end, funnel- shape opening
-forms a pocket around the ovary
-captures the ovulate oocytes
Fimbriae
increases SA
-causes the infundibulum to slip over the entire ovary near ovulation
- maximized chance that oocyte is captured
ampulla
the thick portion of the oviduct
-occupies half for more of the oviduct length
-relatively large in diameter
-many fern-like mucosal folds with ciliated epithelium
Ampullary-isthmic junction (AIJ)
site of fertilization
isthmus
smaller in diameter then the ampulla
-connected to the uterus
-utertubal junction (UTJ)
what is the primary fucntion of the muscularis
oocytes and spermatazoa
-requires movement in opposite direction
mucosa secretes substances that provides
the optimun enviromemnt for the oocytes
-sustains sperm fucntion until oocytes provide
-possibly facilitates feterlizing capability of the spermatoazoa
zygotes resides
in the oviduct before entering the uterus
-fluid secreted must provide a suitable environment fro early embryonic development
UTJ is believed to
regulate movement of the embryo into the utreus in the cow
in swine the UTJ
constricts and serves as a barrier to sperm
-prevents the excessive number from reaching the ampulla
PREVENTS POLYSPERMY
uterus
organ of preganacy
-connects oviducr ro cervix
-has two horns (cornua) in most mammals
what are the three types of uteri
duplex, biocornuate, and simplex