Exam 1- Neuropharm part 1

autonomic nervous system

part of peripheral NS, uncontrolled processes, sympathetic vs parasympathetic

parasympathetic NS

calming, rest and digest

cholinergic drugs

stimulate the parasympathetic nervous system

symptoms of parasympathetic pathway activation

pupils constrict, salivation, slow heart, constrict bronchi, digestion, release bile, secretion, urination

Sympathetic NS

arousal, fight or flight

adrenergic drugs

stimulate the sympathetic nervous system

symptoms of sympathetic NS activation

pupils dilate, inhibit salivation, accelerate HR, dilate bronchi, inhibit digestion, release glucose, release epi and NE, inhibit secretion, relax bladder

Acetylcholine (ACh)

cholinergic receptor

Acetylcholinesterase

breaks down acetylcholine

adrenergic receptors

alpha 1, alpha 2, beta 1, beta 2, and dopamine

alpha 1

vasoconstriction, bladder and stomach constriction, eye constriction

alpha 2

inhibits NE release

beta 1

increase HR

beta 2

increase lungs

dopamine receptors

dilate kidney for urination