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Circulation

The movement of blood and lymph throughout the body, supplying nutrients and oxygen to cells and removing waste.

Sepsis

Blood poisoning caused by circulating agents or toxins, leading to a drop in blood pressure and potentially septic shock.

Lymphangitis

Visible red streaking from an infection site, usually a limb, caused by an infection of the lymphatic vessels.

Red Pulp

Tissue in the spleen consisting of multiple blood-filled passageways that filter and clean the blood.

White Pulp

Lymphoid tissue in the spleen containing B and T lymphocytes.

Acute Bacterial Endocarditis

Sudden onset of fever caused by virulent species such as Staphylococcus aureus or Streptococcus pneumoniae, which can quickly destroy heart valves and lead to heart failure.

Subacute Endocarditis

Slowly progressing form of endocarditis caused by less virulent organisms, which is less likely to be fatal.

Septic Shock

Life-threatening complication of sepsis characterized by decreased urine output, increased respiratory and pulse rates, and cool dusky color in the extremities.

Tularemia

Also known as rabbit fever or deer fly fever, an infection caused by Francisella tularensis, resulting in ulceration, enlarged lymph nodes, fever, and chills.

Brucellosis

Undulant fever or bang disease caused by Brucella species, characterized by gradual onset of fever, sweating, weakness, enlarged lymph nodes, and weight loss.

Plague

A bacterial disease caused by Yersinia pestis, with different forms including pneumonic plague, septicemic plague, and bubonic plague.

Mononucleosis

Also known as the kissing disease, caused by Epstein-Barr virus (EBV) and characterized by fever, sore throat, swollen lymph nodes, and enlarged spleen.

Yellow Fever

A viral disease transmitted by Aedes aegypti mosquitoes, causing symptoms such as fever, jaundice, bleeding, and kidney failure.

Malaria

A protozoan disease caused by Plasmodium species, characterized by flu-like symptoms, cycles of chills, fever, and sweat, and transmitted by Anopheles mosquitoes.

Plasmodium falciparum

A species of protozoan parasite that causes the most severe form of malaria.

Blood Vascular diseases

Diseases that affect the blood vessels, such as atherosclerosis or hypertension.

Acute bacterial endocarditis

Inflammation of the inner lining of the heart caused by bacteria, specifically Staphylococcus aureus and Streptococcus pneumoniae.

Subacute endocarditis

Inflammation of the inner lining of the heart caused by bacteria, specifically Staphylococcus aureus and Streptococcus epidermidis.

Sepsis/septic shock

A life-threatening condition caused by a severe infection, often by Gram-negative bacteria containing lipopolysaccharides (endotoxins). Symptoms include decreased urine output, increased respiratory and pulse rates, and cool dusky color in the extremities.

Bacterial disease of the lymph nodes and spleen

Tularemia, also known as rabbit fever or deer fly fever, caused by the bacterium Francisella tularensis.

Brucellosis

A bacterial infection, also known as undulant fever or bang disease, caused by Brucella species, particularly B. melitensis in goats and sheep.

Category B bioterrorism

A classification for biological agents that are moderately easy to disseminate and have moderate morbidity rates. Osteomyelitis is a rare complication of this category.

Plaque

The causative agent of the Black Death, a severe bacterial infection caused by Yersinia pestis. It is considered a Category A bioterrorism agent.

Yersinia pestis

The bacterium responsible for causing the plague, with virulence factors including PLA, YOPS, and F1.

Viral disease of the lymphoid and blood vascular disease

Mononucleosis, also known as mono or the kissing disease, caused by the Epstein-Barr virus.

Yellow fever

A viral disease transmitted by mosquitoes, specifically the Aedes aegypti species, and characterized by fever and jaundice. It is caused by an RNA arbovirus.

Vector mosquitoes

Mosquitoes that transmit diseases by carrying and transmitting pathogens, such as the Aedes aegypti species for yellow fever.

Protozoan Diseases

Diseases caused by protozoan parasites, such as malaria.

Malaria

A disease caused by various species of the Plasmodium parasite, transmitted through the bite of infected mosquitoes. It is characterized by stages including cold stage, hot stage, and wet stage.

Plasmodium

A genus of protozoan parasites that cause malaria, including species such as Plasmodium vivax, Plasmodium falciparum, Plasmodium malariae, Plasmodium ovale, and Plasmodium knowlesi.