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Bohr Shift
High CO2 conc. —> reduced affinity of Hb to O2 —> dissociation curve shifts RIGHT
Mechanisms of CO2 REDUCING affinity
CO2 + H2O —> H++ HCO3- —> H+ REDUCES pH —> affinity REDUCES
CO2 binds REVERSIBLY to Hb polypeptides —> forms Carbaminohaemoglobin —> lower O2 affinity
Which band shortens?
light (actin ONLY)
low pH blood/ high CO2/ low O2 - signal sent where? and heart rate?
Sympathetic nerve —> SA node - HR: INCREASES
high pH blood/ low CO2/ high O2 - signal sent where? and heart rate?
Vagus nerve —> SA node - HR: DECREASES
Titin connect what to what?
myosin to z-disk