IV SEM B.PHARM PHARMACOLOGY VIVA QUESTIONS: UNIT 2

Vocabulary-style flashcards covering the principles of pharmacodynamics, drug actions, targets, and enzyme inhibition for IV B.PHARM pharmacology students.

Pharmacodynamics

The study of drug effects on the body, specifically what the drug does to the body.

Drug action

The effect produced by a drug that alters physiological function.

Stimulation

A principle of drug action that enhances cellular activity and increases physiological function.

Caffeine

An example of a drug that uses the principle of stimulation to increase alertness.

Depression

A principle of drug action that suppresses cellular activity and reduces physiological function.

Barbiturates

An example of a drug that uses the principle of depression and is used as a sedative.

Irritation

A principle of drug action that causes local stimulation and produces reflex action.

Capsaicin cream

An example of a drug that uses the principle of irritation for pain relief.

Replacement therapy

The process of replacing deficient substances to restore normal function in the body.

Insulin

An example of replacement therapy used in diabetes mellitus.

Cytotoxic action

The process of destroying harmful cells, used against pathogens or tumors.

Chemotherapeutic agents

An example of cytotoxic drugs, including antibiotics, used to destroy harmful cells.

Receptors

Proteins that bind ligands to produce a physiological response; one of the targets of drug action.

Enzymes

Biological catalysts in the body that speed up chemical reactions and serve as drug target sites.

Ion channels

Membrane pores for ions that control ion movement and act as targets for drug action.

Lidocaine

An example of an ion channel blocker used to produce local anesthesia.

Transporters

Proteins present in the cell membrane that transport molecules and can be targets for drug action.

Fluoxetine

An example of a transporter inhibitor used in the treatment of depression.

Enzyme inhibition

The reduction of enzyme activity which blocks chemical reactions.

Non-specific enzyme inhibition

A type of inhibition where a drug acts on many enzymes in a non-selective manner.

Alcohol

An example of a substance that causes non-specific enzyme inhibition by denaturing enzymes.