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medications
substances prescribed for treatment that produce therapeutic effects
drugs
substances used in diagnosis, treatment, or disease prevention, or as a component of medication
generic
common name used by every company for consistent identification
identifies its chemical family
if a drug consists principally of one chemical, it may also be referred to by its chemical name
ex. acetylsalicylic acid is the chemical name for the generic drug aspirin
trade/brand name
given to the drug by its manufacturer
US Food and Drug Administration
FDA
FDA
sets the standards for control of drugs
efficacy
purity
potency
safety
toxicity
5 rules for the standards for drugs set by the FDA
trade name
generic name
chemical composition
chemical strength
usual dose
indications
contraindications
reported side effects
the FDA requires all drug packages include the following:
pharmacokinetics
the study of the way the body processes a drug
includes how drugs are absorbed, distributed to reach their site of action, are metabolized, and exit the body
age
physical condition
gender
weight
immune status
individual responses to medications can vary greatly depending on:
absorption
movement of a drug from the site of administration into systemic circulation to produce the desired effect
distribution
means by which a drug travels from the bloodstream to the target tissue and site of action
metabolism
the body transforms drugs into an inactive form that can be excreted from the body
most occurs in the liver
excretion
elimination of drugs from the body after metabolism.
can be thru kidneys, intestines, lungs, breast milk, or exocrine glands
pharmacodynamics
the study of effects of drugs on the normal physiological functions of the body
therapeutic effect
desired effect, predictable response, results in anticipated outcome
agonist
a drug that produces a specific action and promotes the desired result
antagonist
a drug that attaches itself to the receptor, preventing the agonist from acting
side effect
effect other than what is desired
toxic effect
poisonous, potentially lethal
idiosyncratic effect
overreaction, underreaction, unusual reaction
allergic response
characteristic response to an allergen
synergistic effect
responses to combined drugs that differ from their individual effects
antidote
drug that treats a toxic effect
antimicrobials
suppress the growth of microorganisms
antibiotics
treat wound infections and infectious diseases
anticonvulsants
used to control or prevent seizures
antiarrhythmics
used to prevent or relieve chronic cardiac arrhythmias
analgesics
relieve pain without causing a loss of consciousness
opioid/Narcotic analgesics
are the most effective analgesics, but also have potential for addiction or abuse
respiratory depression
life threatening side effect of opioids/Narcotics
nonsteroidal anti-inflammatory drugs
NSAIDs
NSAIDs
mild to moderate pain relief
reduction of inflammation without steroids
sedatives & tranquilizers
exert a quieting effect, often inducing sleep
not analgesics but may provide relief from pain by promoting muscle relaxation
tranquilizers
reduce anxiety and mental tension more effectively than sedatives and often provide some sedation as well
anesthetics
depress neuronal function, ability to perceive pain and/or other sensations
local anesthetic
injected to eliminate sensation in a specific area
local numbing effect at site of administration
general anesthetics
used during surgical procedures for sedation
causes loss of all body sensation, and some loss of consciousness
paralytic agents
skeletal muscle relaxant
artificial respiration is necessary bc all muscles are temporarily paralyzed
hypoglycemic agents
control the level of glucose in the blood
antihypertensive
reduce blood pressure
angiotensin-converting enzyme (ACE) inhibitors
lower BP by interrupting the enzyme that stimulates the adrenal glands to produce other enzymes that increase BP
primarily used to treat hypertension, but also to treat cardiac failure and renal disease
beta blockers
suppress the action of the sympathetic nervous system by blocking the activity of epinephrine and norepinephrine
used to treat several cardiac conditions (irregular heart rhythm & angina pectoris (chest pain))
antocoagulants
inhibit the clotting mechanism of blood
used to prevent thrombus formation prior to surgery and to prevent thrombi after MI, PE, stroke, & venous thrombosis
antidepressants
relieve or prevent depression
antiemetics
relieve or prevent nausea and vomiting
bronchodilators
dilate smooth muscle, used to treat asthma, COPD, and some allergic reactions. Opens the airways to improve respiration
cathartic/laxative
stimulate peristalsis; promote defecation
diuretics
stimulate the flow of urine; reduce blood volume through urinary excretion of water to treat hypertension
antidiuretic
suppress urine formation
vasodilators
relax the walls of blood vessels, permitting a greater flow of blood
vasoconstrictor
cause blood vessels to constrict, increasing heart action & raising BP
corticosteroids
used to reduce symptoms associated with chronic inflammatory disorders or for the short-term treatment of acute inflammatory conditions
anticholinergics
reduce smooth muscle tone, motility of GI tract, and secretions from the resp. tract and secretory glands
treat over-active bladder
hormones
drugs that affect the endocrine system
antihistamine
relieve allergy symptoms, reduce allergic response