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asthma

emphysema

restriction

variable intrathoracic obstruction

variable extrathoracic obstruction

fixed obstruction
fixed obstruction factors
variable extrathoracic obstruction causes
stridor, vocal cord paralysis, tumor, thyroid enlargement, tracheal malacia (above neck)
variable intrathoracic obstruction causes
swelling, tracheal malacia, bronchial stenosis, scarring, prolonged intubation, radiation therapy (below neck)
x-axis of flow-volume loop
volume (liters)
y-axis of flow-volume loop
flow (liters/sec)
flow-volume loop measured by
spirometry
line in flow-volume loop
flow
RV in flow-volume loop
volume left in lung after forced expiration
TLC in flow-volume loop
volume left in lung after maximal force inhalation
what happens in obstructive lung disease
expiratory curve coves in, RV increases, TLC increases, shift left because of obstruction, inspiration normal (slightly reduced), PEFR decreased
what happens in restrictive lung disease
decreased PEFR, decreased RV, decreased TLC, decreased inspiratory flow, loop shifts right. No cove because no obstruction.
what happens in fixed obstruction
decreased PEFR, increased RV, flattens both inspiratory and expiratory curve (decrease)

normal flow-volume loop
flow-volume loop improves after bronchodilator
asthma, reverse obstruction
flow-volume loop does not improve after bronchodilator
COPD, fixed obstruction