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homeostasis
ability of an organism to maintain its internal environment, despite changes in the external environment
the body uses ____ to maintain homeostasis
feedback mechanisms
two types of feedback mechanisms
negative feedback and positive feedback
negative feedback
when the response stops the stimulus
positive feedback
when the response increases the stimulus
what does your body need to keep stable
body temperautre, blood pressure, blood pH, O2 and CO2 concentration, water balance, and blood glucose
what are the 2 main body systems involved in homeostasis
endocrine and nervous system
endocrine system
series of glands that produce hormones to help maintain homeostasis, attempt at long term stability, a lower response than nervous stability
nervous system
The coordinating centre comprised of the spinal cord and brain, attempts at short-term stability, immediate response
organs of excretory system
kidneys, bladder, and liver
kidneys
water-soluble waste is formed here, as well as regulation of body pH and water levels
bladder
stores liquid waste
liver
transforms ingested toxins such as alcohol, heavy metals and waste from protein metabolism into soluble compounds that can be removed by the kidney
types of water soluble wastes
ammonia and urea
ammonia
produced by protein and DNA metabolism, it is very toxic so the liver converts it to urea
urea
100,000x less toxic than ammonia
urinary system components
renal arteries, renal veins, ureters, urinary sphincter, urethra
renal arteries
pass blood to kidneys
renal veins
remove blood from kidneys
ureters
pass urine to the bladder
urinary sphincter
controls the release of urine from bladder
urethra
the tube used to void the bladder
kidney structure components
cortex, medulla, and renal pelvis
cortex
outer layer of connective tissue of kidney
medulla
inner layer under the cortex in kidney
renal pelvis
hollow chamber which connects the kidney with the ureter
nephron
approxim ately one million small functional units of the kidney spanning the cortex and the medulla, comprised of specialized blood vessels and tubes that wrap around each other for filtering wastes from the blood and producing urine
where does making urine occur
nephrons
first step of making urine
filteration
filteration
occurs from the glomerulus to bowman’s caspule, anything small (urea) moves by difusion into bowman’s capsule
step 2 of making urine
reabsorption
reabsorption
put non-waste materials back into blood
where does glucose go in reabsorption
proximal convulated tubule
last step in making urine
secretion
secretion
occurs from PCT to DCT, maintains ion and water levels by returning excess amounts to he nephron from blood
where does water go in reabsorption
descending loop of henle
where do H+ go in reabsorption
distole convulated tubule
blood flow
renal arteries—>afferrent —> glomerulus —> efferent arteriole —> capillaries —> renal vein
flow of glucose
renal artery —> afferent artirole —> glomerulus —> bowman’s capsule —> proximal convulated tubule —> capillaries —> renal vein
afferent
carry blood toward an organ
efferent
carry blood away from an organ
what is in the blood before it enters the kidney
urea, glucose, water, NaCl, H+, K+, RBC, WBC,platelets, protein
what is in the nephron in the bowman’s capsule/glomerulus
urea, glucose, water, NaCl, H+, K+
what is in the nephron in the proximal tubule
urea, water, NaCL, H+, K+
what is in the nephron in the loop of henle
uea, H+, K+, water
what is in the nephron in the distal tubule
urea and water
what is in the nephron in the collecting duct
urea and water
the nervous system
a communication system
divisons of the vertebrae nervous system
central nervous system and peripheral nervous system
central nervous system
brain, spinal cord, coordinating centre
peripheral nervous system
nerves that carry info between the receptors, CNS, and the organs/muscles
sections of peripheral nervous system
afferent system and efferent system
afferent system
recieves input from receptors and transmits it to CNS
efferent system
carries signals to effectors (muscles and glands)
types of efferent systems
somatic nerves and autonomic nerves
somatic nerves
voluntary processes
autonoic nerves
involuntary processes
sections of autonomic nerves
sympathetic and parasympathetic
sympathetic
prepares body for action (heartrate, breathing, sweating, pupil dilation)
parasympathetic
stimulates body activities that acquire and conserve energy (digestion)
types of nervous system cells
neurons and glial cells
neurons
cells that conduct nerve impulses (functional units)
glial cells
structural support and metabolism of nerve cells (do not conduct messages)
nerve
bundle of many neurons
neuron anatomy
cell body, dendrites, axon, myelin sheath, schwann cells, nodes of ranvier, and neurilemma
cell body of neuron
nucleus and majority of cytoplasm
dendrites
projections of cytoplasm that carries nerve impulses to the body
axon
extension of cytoplasm that carries nerve impulses away from the body
myelin sheath
insulated covering (made of fat) over the axon of some nerves, preents loss of charge
schwann cells
type of glial cell that produces myelin sheath
nodes of ranvier
regularly occuring gaps between sections of the myelin sheath
neurilemma
thin membrane surrounding the axon in PNS, promotes regeneration of damaged axons
which nervous system has a greated ability to regenerate
peripheral nervous system
neurons without ___ or ____ do not regenerate
myelin sheath or neurilemma
grey matter
in brain and spinal cord, no myelin sheath, fast signal, no repair
white matter
has myelin sheath, slower signal, can repair
types of neurons
sensory neurons, motor neurons, and interneurons
sensory neurons
afferent neurons, carry impusles from sensory receptors to the central nervous system
motor neurons
efferent neurons, carry impulses from the central nervous sytem to effectors (muscles, organsm, glands… things that produce a response)
interneurons
relay neurons, link sensory neurons to moto neurons with the body, found in the central nervous system
the reflex arc
neutral circuit through the spinal cord that provides a framework for a reflex action, the simplest nerve pathway, involuntary, unconscious
what happens when your hand accidentally touches a hot stove
heat is detected by thermoreceptors in skin, nerve impulse is carried by sensory neurons to spinal cord, interneurons send singal to brain to make a conscious decision about any further actions required, motor neurons carry impulse to muscles in hand, signal causes muscles to pull hand away
resting potential
the cell membrane has a potential diffrent across the membrane, there is an overall negative charge
polarization
negative charge inside (-70mV), Na+ on outside K+ on inside
3 ways to depolarize a membrane
a stimulus arriving at a receptor cell, a chemical fitting into a receptor site, or a nerve impulse travelling down a neuron
depolarization
positive charge on inside Na+ diffuse to inside
action potential
the state of the neuron when a nerve impulse passes by (35mV)
threshold potential
-55mV
repolarization
negative charge on inside K+ moves from inside to outside, Na+ is inside
hyperpolarization
negativ charge on inside (below -70mV) Na+ on inside K+ on outside
refractory period
gradual active pumping of the ions (3 Na+ out 2 K+ in at a time) to restore resting potential, during this period no impulses can pass along that part of the membrane
how many ions does the sodium-potassium pump move
3 Na+ out 2 K+ in
first step of action potential
sodium channels open
step in action potential after sodium channnels open
sodium ions diffuse into cell (depolarization)
step in action potential after depolarization
sodium channels close while potassium channels open
step in action potential after potassium channels open
repolarization - potasssium diffuse to outside
last step of action potential
active transport is used to move potassium into the the ion and sodium out
why does the neuron become hyper polar
potassium channels are slow to close
the meninges
3 protective membranes that surround the brain and spinal cord, act as protection and support the CNS
blood brain barrier
most substances cannot leave blood stream and enter cerebrospinal fluid