Omnipod 5 Automated Insulin Delivery System Review

These vocabulary flashcards cover the essential components, operating modes, safety warnings, and clinical evidence for the Omnipod 5 Automated Insulin Delivery System.

Omnipod 5 Automated Insulin Delivery System

A single-hormone insulin delivery system intended to deliver $U-100$ insulin subcutaneously for the management of type 1 diabetes in persons aged 2 and older.

Automated Mode

A mode that modulates (increases, decreases, or suspends) insulin delivery every $5\,minutes$ using current and predicted sensor glucose values to maintain Target Glucose levels.

Manual Mode

An operating mode that delivers insulin at set Basal Programme rates or manually adjusted rates.

Compatible Insulins

NovoLog/NovoRapid, Humalog, Admelog/Insulin lispro Sanofi, Trurapi/Insulin aspart Sanofi, and Kirsty $U-100$ insulin.

Hydroxyurea Contraindication

The system is not recommended for people taking hydroxyurea while using a Dexcom Sensor, as it could lead to falsely elevated sensor values and over-delivery of insulin.

Electronic Procedure Precautions

The Pod, Sensor, and Transmitter must be removed before Magnetic Resonance Imaging (MRI), Computed Tomography (CT) scan, or diathermy treatment.

Omnipod ID

A required identifier and password used to complete Omnipod 5 onboarding and App setup.

Automated: Limited

A system state where the Pod is not receiving sensor glucose values; the system uses the lower of the Automated Adaptive Basal Rate and the Manual Basal Programme.

SmartBolus Calculator

A tool that uses carbs, sensor glucose values, trend arrows, and Insulin on Board ($IOB$) to calculate a suggested bolus dose.

Adaptive Basal Rate

A continuous baseline insulin delivery that the system adjusts every $5\,minutes$ in response to sensor glucose values and is updated with every Pod change.

Activity Feature

A feature available only in Automated Mode that sets the Target Glucose to $8.3\,mmol/L$ ($150\,mg/dL$) and reduces insulin delivery for times of decreased insulin needs, like exercise.

Line of Sight

A placement strategy where the Pod and Sensor are worn on the same side of the body so they can communicate without the body blocking the signal.

Hazard Alarms

High-priority alarms (e.g., Blockage Detected, Pod Expired, Pod Out of Insulin) that indicate a serious problem has occurred and insulin delivery has stopped.

Advisory Alarms

Lower-priority alarms (e.g., Low Pod Insulin, Start Insulin, Missing Sensor Values) that alert the user to conditions requiring attention.

Pod IP28 Rating

An ingress protection rating indicating the Pod is waterproof to a depth of up to $7.6\,metres$ ($25\,feet$) for up to $60\,minutes$.

Controller IP22 Rating

An ingress protection rating indicating the Controller is protected from fingers but is not well-protected from water and should avoid liquid.

Extended Bolus

A bolus feature available only in Manual Mode that allows for insulin delivery over a user-selected period of time.

Temp Basal

A temporary change to the basal rate for illness or activity, available only in Manual Mode.

Target Glucose and Correct Above

The only Automated Mode settings that can be changed to impact automated insulin delivery ($6.1\,mmol/L$ to $8.3\,mmol/L$).

Blockage (Occlusion)

An interruption in insulin delivery from the Pod; a hazard alarm sounds when an average of $3$ to $5\,units$ of missed insulin occurs.

Hypoglycaemia Threshold

Glucose below $3.9\,mmol/L$ ($70\,mg/dL$) with symptoms like shakiness, fatigue, hunger, and sweating.

Hyperglycaemia Threshold

Glucose readings $\geq 13.9\,mmol/L$ ($250\,mg/dL$) which may require checking for ketones.

Pivotal Study Outcomes

Adolescents, adults, and children experienced improvements in overall $A1C$ and sensor glucose time in range ($3.9\text{--}10\,mmol/L$) after 3 months of use.