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Forensic Autopsy
Required to determine cause and manner of death, especially in sudden, unexpected, or suspicious cases.
Diagnostic Test Selection
Beneficial to know patient’s medical history, symptoms, and clinical information to reduce false positives.
Pharmacogenomics
Study of how genes influence response to drugs, combining pharmacology and genomics for tailored medications.
SOP
Standard Operating Procedure.
External Examination
Initial step in forensic autopsy, examining body’s physical characteristics, marks, injuries, or diseases.
Toxicological Analysis
Used if victim is suspected of being poisoned, testing body fluids and tissues for toxins or drugs.
Mortis
Latin term meaning “of death”.
Importance of SOP
Crucial for accuracy, consistency, reliability, quality control, and safety in diagnostic tests.
Calling Authorities
Police should be called if a body is found to secure the scene and initiate an investigation.
Forensic Anthropologist
Called for analyzing partial skeletons to determine age, sex, stature, and cause of death.
Centrifuge
Used to separate sample components based on densities by spinning at high speed.
Forensic Toxicologist
Tests tissue samples and body fluids from autopsies to determine poisoning.
Livor Mortis
Postmortem lividity, helps determine death position by blood pooling due to gravity.
Rapid Diagnostic Tests
Examples include pregnancy tests, glucose tests, and rapid strep tests.
CLIA
Clinical Laboratory Improvement Amendments of 1988 for technical standards and guidelines.
Stomach Contents
Useful in autopsies for last meal information and estimating time of death.
Hair Root
Contains DNA for genetic testing and information on drug use or toxin exposure.
Rigor Mortis
Body stiffening typically observed between two to six hours after death.
Pelvis Width
Helps determine biological sex in forensic anthropology.
Rigor
Latin term for stiffness.
Ossification
Used to determine the age of an individual at the time of death.
Chromosomes
Humans have 23 pairs of chromosomes.
Noninvasive Monitoring
Ultrasound and x-ray are noninvasive methods for disease monitoring.
Hair Samples Limitation
Provides long-term substance use information, not suitable for recent use or extensive DNA.
GINA
Genetic Information Nondiscrimination Act allows knowing inherited traits without discrimination risk.
Detective Scenario
Rigid face and upper arms suggest death occurred approximately 12-24 hours ago.
FDA
Regulates home medical tests.
Urine Sample Inspection
Involves visual examination, chemical analysis, and microscopic examination.
Reference Range
Set of values to interpret lab results for normality.
Karyotyping
Technique for examining an organism’s chromosome set.
Culture and Sensitivity Tests
Determine the best antibiotic for treating infections by growing microorganisms.
Autopsy and Religious Beliefs
Autopsy may be performed against family wishes in sudden, suspicious, or criminal deaths.
Forensic Entomologist
Contacted to analyze eggs or larvae on a body for time of death estimation.
CLIA Impact
Ensures proper training, instrument calibration, and accurate tests.
Medical Examiner
Typically a forensic pathologist specializing in disease and injury study in the deceased.
Patient Identification
Barcodes, bracelets, and personal information improve patient identification.
Least Invasive Sample
Hair is the least invasive sample for a toxicology report.
Rapid Diagnostic Tests
Used in rural settings where lab testing is limited.
Matching Careers