[PCOG-LEC-FIN-02-PT7] PEPTIDE HORMONES & THE ENDOCRINE SYSTEM

THIS FLASHCARDS IS ABOUT [PCOG] PITUITARY GLAND (ANTERIOR) PT2.

Human Chorionic Gonadotropin (HCG)

This anterior pituitary gland is a gonad-stimulating polypeptide hormone obtained from the urine of pregnant women.

Urine

Human Chorionic Gonadotropin (HCG) is a gonad-stimulating polypeptide hormone obtained from the ____ of pregnant women.

Luteinizing Hormone

Human Chorionic Gonadotropin (HCG) resembles __________ hormone in its response.

Choriogonadotropin

Human Chorionic Gonadotropin (HCG) is also known as?

1. Cryptorchidism

2. Interstitial cells

3. Hypogonadotropic eunuchoidism

4. Menotropin

5. Corpus luteum

Uses of Human Chorionic Gonadotropin (HCG):

Replacement therapy to

• Stimulate descent of the testes in (1)________.

• Stimulate the development of (2)_____ cells of the testes in delayed adolescence and (3)__________ eunuchoidism.

• Conjunctive therapy with (4)_____ to treat infertility and maintain the functional integrity of (5) Corpus _____ in some cases of habitual abortion.

Cryptorchidism

This is the most common genital abnormality in baby boys, where one or both testes fail to descend into the scrotum before birth.

• Menotropin

• Gonadorelin

What are the (2) Gonadotropin Related Products?

Hint: Me-Go

Menotropin

This is a purified preparation of gonadotropins obtained from the urine of postmenopausal women that contains approximately equal amounts of FSH and LH.

1. Gonadotropins

2. Urine of postmenopausal women

Menotropins is a purified preparation of (1)_____ obtained from the (2)_____ of postmenopausal women that contains approximately equal amounts of FSH and LH.

Uro gonadotropin

Menotropin is also known as?

1. Fertility

2. Spermatogenesis

Uses of Menotropins:

• Enhance (1)_____ in an anovulatory women with functional ovaries.

• Stimulates (2)_____ in Hypogonadotropic males.

Gonadorelin

This is a synthetic decapeptide that is identical to the gonadotropin-releasing factor of the hypothalamus.

Gonadotropin-releasing factor

Gonadorelin is identical to the ____________________ of the hypothalamus.

Gonadorelin

This is a diagnostic aid in suspected gonadotropin deficiency to evaluate the functional capacity and response of the gonadotropes of the anterior pituitary.

1. Gonadotropin deficiency

2. Gonadotropes

Gonadorelin is a diagnostic aid in suspected (1)_____ deficiency to evaluate the functional capacity and response of the (2)_____ of the anterior pituitary.

Growth Hormone

This anterior pituitary gland stimulates linear growth of bones during development.

• Somatropin

• Somatotropin

• Human Growth Hormone

Growth Hormone is also known as (3)?

hint: SSH

Somatrem

What is the synthetic form of growth hormone?

1. Amino acids

2. N, P, and K

Anabolic Effects of Growth Hormone:

• Increased intracellular transport of (1)_____.

• Net body retention of (2)__,__,__.

Dwarfism

Disorders: Growth Hormone

Hypofunction of the growth-stimulating activity in children.

Acromicria

Disorders: Growth Hormone

A condition in which the bones of the face and limbs (atrophy: lower extremities) are small and delicate due to GH deficiency.

Acromegaly

Disorders: Growth Hormone

Abnormal growth of the hands, feet, and face, caused by overproduction of growth hormone by the pituitary gland.

Thyrotropin

This anterior pituitary gland is the thyrotropic principle of the anterior pituitary. A glycoprotein in the 28k to 30k MV range.

Thyroid-stimulating hormone

Thyrotropin is also called as?

Thyrotropin

This is used as a diagnostic aid in evaluating thyroid function. Also used as supportive therapy to facilitate the uptake of Iodine 131 in treatment of toxic goiter or thyroid carcinoma.

1. Iodine 131

2. Toxic goiter

3. Thyroid carcinoma

Thyrotropin is used as a supportive therapy to facilitate the uptake of (1)_____ in treatment of (2) toxic _____ or (3)_____ carcinoma.

Protirelin

What is the synthetic form of thyrotropin?

Protirelin

This is used as a diagnostic aid to distinguish secondary and tertiary hypothyroidism.

Secondary and Tertiary Hypothyroidism

Protirelin is used as a diagnostic aid to distuinguish?

Thyroid gland

The primary refers to the failure of?

Pituitary gland

The secondary refers to the failure of?

Hypothalamus

The tertiary refers to the failure of?

Primary and Secondary Hypothyroidism

Thyrotropin is the one that distinguishes the?

Thyrotropin

This is the one that distinguish the primary and secondary hypothyroidism.