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Effector molecules encoded by interferon-stimulated genes induce the antiviral state. Which of the following is not a feature of the antiviral state?
A. Enhanced mitosis
B. RNA degradation
C. Blockade of endocytosis
D. Inhibition of protein translation
A. Enhanced mitosis
2. An extracellular pathogen is most likely to be recognized by which of the following pattern recognition receptors?
A. Nod-like receptor (NLR)
B. RIG-I-like receptor (RLR)
C. Toll-like receptor (TLR)
D. CGAS receptor
C. Toll-like receptor (TLR)
3. 3a, C4a, and C5a induce which of the following effector functions?
A. Opsonization
B. Immune complex formation
C. Membrane attack complex formation
D. Anaphylatoxin-induced inflammation
D. Anaphylatoxin-induced inflammation
Which of the following is not a function of traditional chemokine receptors?
Pro-survival signaling
Ligand scavenging
Cytoskeletal reorganization
Induction of gene expression
Ligand scavenging
5. Which of the following pathways of complement fixation is initiated by antibodies?
Lectin
Classical
Modern
Alternative
Classical
6 Which of the following modalities of cell death is characterized by the maintenance of cell membrane integrity after death?
A Necrosis
B Necroptosis
C Apoptosis
D. Pyroptosis
C Apoptosis
Claudin, ZO-1, and Occludin constitute which of the following?
Tight junctions, a physical barrier to infection
Tight junctions, a chemical barrier to infection
Defensins, a physical barrier to infection
Defensins, a chemical barrier to infection
Tight junctions, a physical barrier to infection
8. Which of the following cell types uses specialized granules that enhance the function of phagolysosomes?
A. Tcells
B. Macrophages
C. Mast cells
D. Neutrophils
D. Neutrophils
What type of molecule is STAT?
Receptor
Kinase
Cytokine
Transcription factor
Transcription factor
10. Interleukin-2 (IL2) promotes proliferation of cytotoxic T cells for clearing viral infection.
IL2 also promotes proliferation of regulatory T cells for immune tolerance. This is an example of which of the following?
Pleiotropy
Synergy
Redundancy
Antagonism
Pleiotropy