Exam 1 PollEv
Call Kai
Learn
Practice Test
Spaced Repetition
Match
Flashcards
Knowt Play1/25
There's no tags or description
Looks like no tags are added yet.
Name | Mastery | Learn | Test | Matching | Spaced | Call with Kai |
|---|
No analytics yet
Send a link to your students to track their progress
26 Terms
Amino acids are connected via ___ bonds, which occur between the carboxyl group of one amino acid and the amino acid group of another?
Peptide
3 multiple choice options
During translation, which enzyme attaches the appropriate amino acid onto its tRNA?
Aminoacyl-tRNA synthetase
3 multiple choice options
Which antibiotic acts as a charged-tRNA analog, causing the premature release of the growing peptide chain from the ribosome?
Puromycin
3 multiple choice options
Which of the following statements about protein folding is incorrect?
Protein folding diseases usually occur when beta-sheets misfold and precipitate into alpha-helices
3 multiple choice options
What does it mean when a protein "binds" to another molecule?
The protein temporarily associates with the molecule through weak, noncovalent interactions
3 multiple choice options
IgG consists of
Two light chains and two heavy chains joined by disulfide bonds
3 multiple choice options
Which of the following are co-factors?
All of the above
3 multiple choice options
The transition state of a catalyzed reaction is
Lower in energy than that of an uncatalyzed reaction
3 multiple choice options
What does a small Km indicate?
The enzyme requires only a small amount of substrate to become saturated
3 multiple choice options
Which of the following statements is correct?
Proteases break covalent bonds
3 multiple choice options
Which of the following statements is incorrect?
Restriction endonucleases break peptide bonds
3 multiple choice options
Which of the following statements is correct?
Myosins harness the free energy of ATP hydrolysis to drive other processes
3 multiple choice options
A feedback inhibitor is a(n) ___ that inhibits a(n)
End product; enzyme
3 multiple choice options
Which of the following enzyme regulatory strategies is irreversible?
Proteolytic activation
3 multiple choice options
An inhibitor binds non-covalently to an allosteric site and induces a change in protein structure the enzyme can no longer bind substrate in the active site. What type of inhibition is being described here?
Competitive
3 multiple choice options
Inhibitor A increases the apparent KM without affecting Vmax, whereas Inhibitor B decreases the values of KM and Vmax. What type of inhibitors are Inhibitors A and B?
Competitive; uncompetitive
3 multiple choice options
What is one advantage of a non-competitive inhibitor as a potential drug compared with a competitive inhibitor?
A noncompetitive inhibitor functions independently if substrate concentrations
3 multiple choice options
Which of the following statements is correct?
Indinavir is an HIV protease inhibitor
3 multiple choice options
Some serine protease inhibitors are used as anticoagulant drugs.
True
1 multiple choice option
In the formation of Acetyl CoA from pyruvate, Coenzyme A is a prosthetic group
False
1 multiple choice option
A novel CRISPR- Cas9 based gene knockout therapy is in development with the goal of decreasing Protein X in the liver. To have therapeutic benefit, liver levels of Protein X must decrease by at least 75%. If protein X has a half life of 1 day, how long after successful knockout of the gene encoding protein X will a patient begin to have therapeutic benefit?
2 days
3 multiple choice options
Burkitt Lymphoma is a cancer driven by mutation in the onco-protein c-Myc. Which of the following is likely to be true about c-Myc mutations found in this cancer?
They block ubiquitination sites on the protein
3 multiple choice options
Which of the following is a plausible mechanism for why Bortezomib is effective in multiple myeloma?
Increases levels of pro-apoptotic protein factors
3 multiple choice options
In a patient with a folic acid deficiency, what synthetic form of folic acid is optimal for this person to receive?
Monoglutamated
3 multiple choice options
How is 5,10-methyleneTHF generated in the mitochondria transported to the cytoplasm for biosynthetic processes in that cellular compartment that require this form of a one-carbon unit?
Broken down and resynthesized
2 multiple choice options
If a cancer cell line is growing in folic acid supplemented culture media and then is suddenly switched into folic acid-free culture media, how would you predict the levels of serine and glycine would change?
Serine increase and glycine decreases
3 multiple choice options