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Mental Health
Successful performance of mental function leading to productive activities, fulfilling relationships, and effective coping with adversity
Mental Illness
Diagnosable mental disorders involving alterations in thinking,mood, or behavior that cause distress and/or impaired functioning
Mental Health Problems
Signs and symptoms that do not meet full diagnostic criteria but are still important and warrant preventive efforts
Continuum
mental health ←→ mental health problems ←→ mental illness
Fear
Immediate, acute response to a real, present threat (e.g., snake on a trail);focused on the present
Anxiety
Anticipatory worry about potential future threats; often ruminative and focused on "what if" scenarios
State Anxiety
Transient feelings of worry or tension in response to a situation
Trait Anxiety
General tendency to respond with anxiety across many situations
Clinical anxiety is distinguished from "normal" anxiety by
- Severity and number of symptoms
• Duration and frequency of symptoms
• Degree of suffering and functional impairment
• Symptoms that may occur without a clear trigger, are disproportionate, and feel unmanageable
Diagnostic criteria (e.g., DSM-5, ICD-10
specify that clinical anxiety disrupts normal functioning
Panic disorder
An anxiety disorder marked by unpredictable minutes-long episodes of intense dread in which a person experiences terror and accompanying chest pain, choking, or other frightening sensations.
Agoraphobia
fear or avoidance of situations, such as crowds or wide open places, where one has felt loss of control and panic
Generalized anxiety disorder
a disorder characterized by chronic excessive worry accompanied by three or more of the following symptoms: restlessness, fatigue, concentration problems, irritability, muscle tension, and sleep disturbance
Post-traumatic stress disorder (PTSD)
an anxiety disorder characterized by haunting memories, nightmares, social withdrawal, jumpy anxiety, and/or insomnia that lingers for four weeks or more after a traumatic experience
Obsessive-compulsive disorder (OCD)
an anxiety disorder characterized by unwanted repetitive thoughts (obsessions) and/or actions (compulsions)
Key features of anxiety
• Physical symptoms (e.g., palpitations, shortness of breath)
• Cognitive symptoms (e.g., fear of dying, fear of losing control)
• Behavioral responses (e.g., avoidance, escape)
Comorbidity
the co-occurrence of two or more disorders in a single individual
Most common anxiety disorder
generalized anxiety disorder (GAD)
Cognitive Anxiety
worry, self-doubt, difficulty concentrating, catastrophic thinking
Bodily/physiological anxiety
muscle tension, autonomic arousal, sweating, rapid heart rate
Behavioral Anxiety
avoidance, escape behavior, hypervigilance
Anxiety Medication
o Benzodiazepines (tranquilizers) and antidepressants (e.g., SSRIs).
o Benefits: Symptom reduction for many individuals.
o Limitations: Side effects, withdrawal symptoms, cost, adherence issues, not effective for everyone.
Psychotherapy
o Cognitive-behavioral therapy (CBT) and related approaches.
o Benefits: Strong evidence base; can modify maladaptive cognitions and behaviors.
o Limitations: Access barriers (cost, time, provider availability).
Anxiolytic
anxiety reducing
Acute exercise
Single bouts of moderate-intensity exercise can reduce state anxiety for several hours
Chronic exercise
Regular exercise is associated with lower trait anxiety and reduced risk of developing anxiety problems
Depressed mood
Persistent feelings of sadness, emptiness, or "numbness."
MDD diagnosis (DSM-5 framework)
o At least five symptoms present for at least two weeks.
o Must include either depressed mood or markedly diminished interest/pleasure (anhedonia).
o Symptoms can include changes in appetite/weight, sleep disturbances,psychomotor changes (slowing or agitation), fatigue, feelings of worthlessness or guilt, concentration difficulties, and recurrent thoughts of death or suicide
Melancholic features
Loss of pleasure, early-morning awakening, significant weight loss, psychomotor slowing
Atypical features of depression
Increased appetite/weight gain (hyperphagia), hypersomnia,mood reactivity
Psychomotor slowing vs. agitation
Both can appear in depression; agitation often linked to anxious distress
Classification approaches of depression
o Clinician-administered diagnostic interviews (DSM-5 based).
o Self-report scales with diagnostic cutoffs (e.g., PHQ-9 score ≥ 10)
Continuous approaches of depression
o Self-report scales used as continuous symptom severity measures (e.g. Hamilton Depression Rating Scale, Geriatric Depression Scale).
Monoamine hypothesis and limitations
o Proposed that depression results from deficiencies in serotonin, norepinephrine, dopamine.
o Now seen as incomplete; depression involves complex interactions among neurotransmitters, genetics, environment, and plasticity.
BDNF (Brain-Derived Neurotrophic Factor)
o Lower BDNF levels observed in depression.
o Exercise and some antidepressants increase BDNF, supporting neuroplasticity
Resting-state functional connectivity in MDD
o Hyperconnectivity within the default network (DN) → excessive internally focused, ruminative thinking.
o Hypoconnectivity within frontoparietal control networks (FN) → weaker cognitive control.
o Altered connectivity between control, attention, and affective/salience networks (e.g., DAN, AN, VAN)
Exercise as Treatment for Depression
o Randomized controlled trials show regular exercise can reduce depressive symptoms.
o Effects often comparable to medication and psychotherapy for mild-to-moderate depression when adherence is good.
o Guidelines from professional organizations now include exercise as an evidence-based option (stand-alone or adjunct)
Key issues with exercise
• Dose parameters: Frequency, intensity, session duration, program length.
• Clinical vs. nonclinical samples.
• Importance of adherence and support when using exercise as treatment
James-Lange Theory of Emotion
• Emotions result from interpretation of bodily responses to events (we feel afraid because our heart is racing)
Distinguishing Affect
o General valenced feeling (pleasant-unpleasant) that may not require cognitive appraisal.
o Immediate, reflexive reactions (e.g., unpleasantness to pain)
Distinguishing emotion
o Short-lived, often high-intensity responses to specific stimuli or events.
o Typically involve cognitive appraisal ("I'm anxious because I have to give atalk").
Distinguishing moods
o Longer-lasting, lower-intensity feeling states.
o More diffuse, may not have a clear identifiable cause.
o Linked to ongoing behavior and cognition
POMS (Profile of Mood States)
o 65 adjectives → six mood subscales (tension-anxiety, depression-dejection, anger-hostility, vigor-activity, fatigue-inertia, confusion-bewilderment).
o Widely used but treats mood as discrete categories
PANAS (Positive and Negative Affect Schedule)
o Two independent dimensions: Positive Affect and Negative Affect.
o Captures high-activation states (e.g., excited, jittery, scared).
o Limitation in exercise context: Less sensitive to low-activation states (calm, relaxed, tired)
AD ACL (Activation-Deactivation Adjective Check List) Measures
▪ Energetic arousal (energy ↔ tiredness)
▪ Tense arousal (tension ↔ placidity)
o Can be mapped into quadrants combining valence and arousal
Dimensional and Circumplex Models
o Affect represented along valence (pleasant-unpleasant) and activation(high-low) dimensions.
o Helps map states like energized, calm, tense, fatigued
Exercise-Specific vs. Generic Measures
o Several exercise-specific scales exist, but so far they do not clearly outperform well-validated generic measures.
o Key takeaway: Circumplex-based and other validated generic scales work well.
Acute Exercise and Affect Typical patterns
- Moderate-intensity exercise → increased positive affect and reduced negative affect for most people, especially post-exercise.
• High-intensity exercise (especially above ventilatory threshold) can feel unpleasant during the bout but may still lead to improved affect afterward in many individuals
Acute Exercise and Affect Individual differences
• Intensity-preference: Preferred intensity when given choice.
• Intensity-tolerance: Ability to continue at an imposed intensity even when uncomfortable.
• Low tolerance at high intensities → more negative affective responses
Regular physical activity is associated with
Higher positive affect and vigor.
• Lower negative affect and fatigue.
• Better general emotional well-being, even in nonclinical samples
What Is Cognitive Function?
• Processes by which individuals perceive, recognize, and understand thoughts and ideas.
• Includes perception, attention, learning, memory, and planning/executing goal-directed behavior.
Age-related changes
Decreases in gray and white matter volume with age.
• Particularly notable changes in prefrontal cortex and hippocampus.
• Slowed processing speed and declines in some executive functions.
Cognitive tasks used in research
• Stroop, flanker, task-switching paradigms, n-back, Trail Making, memory tasks.
• Be able to recognize which tasks tap executive control processes
Cross-sectional evidence
• Higher-fit older adults tend to perform better on tasks requiring executive control.
• They show more efficient activation in attentional networks compared to lower-fitpeers
ERPs - P3 component
• P3 amplitude: allocation of attentional resources and working memory updating.
• P3 latency: speed of processing.
• Higher fitness and acute exercise often associated with larger P3 amplitude and/orshorter latency → more efficient processing