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What is Cost Effectiveness Analysis (CEA)?
CEA is a method used in healthcare to compare costs and health results of two or more treatments/programs.
👉 It helps answer:
“Which treatment gives better results for the money spent?”
Main Idea of CEA
It compares:
Cost = How much money is spent
Effectiveness = How well it works
Examples of effectiveness:
Cases prevented
Life years gained
Symptom-free days
Patients cured
Why Do We Use CEA?
1. Compare two or more programs/treatments with same outcome
Example: Compare Drug A vs Drug B for ulcer treatment.
2. Decide if expanding a program is worth the cost
Example: Should hospital vaccinate more people?
Formula of Cost Effectiveness Ratio
Cost / effectiveness
Example:
If Drug costs $100 and cures 10 patients:
= 100 / 10 = $10 per patient cured
👉 Lower ratio = Better value
CEA vs CUA
CEA:
Measures cost compared with health outcomes.
Examples:
Cost per case prevented
Cost per life year gained
CUA (Cost Utility Analysis):
Special type of CEA that also includes quality of life.
Uses QALY = Quality Adjusted Life Year
👉 Measures both longer life + better quality life.
Advantages of CEA
Easy to understand
✅ Uses results already measured in clinical trials
✅ Helpful for doctors and policymakers
Disadvantages of CEA
Cannot compare very different diseases easily
Example:
You cannot compare:
Blood pressure drug
with
Asthma inhaler
Because outcomes are different.
What is ICER?
CER = Incremental Cost Effectiveness Ratio
Used to compare new treatment vs old treatment
Shows:
👉 Extra cost for extra benefit
ICER= ( C2-C1)/ ( E2-E1)
C₂ = Cost of new treatment
C₁ = Cost of old treatment
E₂ = Effectiveness of new treatment
E₁ = Effectiveness of old treatment
EXAMPLE:
ICER of C compared with B:
( 530-210)/(250-200)= 6.40
= $6.40 per extra symptom-free day
Meaning:
Drug C costs $6.40 more for each extra symptom-free day compared to B.
Dominant vs Dominated
Dominant Treatment:
✅ Cheaper
✅ More effective
Best choice.
Dominated Treatment:
❌ More expensive
❌ Less effective
Bad choice.
If ICER gives negative values, often one option is dominant.
How to Interpret ICER?
Ask:
👉 Is the extra benefit worth the extra cost?
If yes = choose new treatment
If no = keep old treatment