ALL DRUGS PREmidterm

weeks 1-7

ibuprofen(generic) 4 ex (brand)

advil, motrin, brufen, nurofen

what is betamethasone used for

glucocorticoid used in intra-articular injection for osteoarthritis

5 drugs that are absorbed in stomach

etoh

caffeine

asa

warfarin

dilantin

7 extensively first pass metabolism drugs

morphine

meperidine

diazepam

midazolam

lidocaine

nitroglycerine

thc

demerol - what is generic name

meperidine

valium what is the generic name

diazepam

7 extensively bound drugs (ppb > 90%)

warfarin

ibuprofen

naproxen

furosemide

digitoxin/digitalis (this is the drug class, NOT ENTIRELY PPB)

diazepam

midazolam

warfarin drug class and what does it do

anticoagulant ( blood thinner)

ibuprofen and naproxen drug class

nsaids

lasix(brand) what is its generic name

furosemide

furosemide drug class and importnat feauture

loop diureticover 90% ppb

wnat opt to frrquenly urinate (decrease edma or get ride of fluid for congestive heart failure)

digitoxin drug class and what is important to remember

cardiac (manages heart failure)

over 90% ppb bound

diazepam and midazolam drug class

benzodiazepines

valium generic name

diazepam

tylenol generic name

acetaminophen

3 zero order elimination drugs

ethanol (etoh), aspirin (asa), phenytoin (dilantin)

what is buprenorphine used to treat

moderate opiod

what receptor type does lidocaine travel through

ion channels

3 drugs that build a drug tolerance (down regulation)

cns substances (opiates, benzodiazepine, alcohol)

what do benzodiazepines drug class treat

anxiety, panic attacks, seizures, insomnia, seizure

4 narrow t1 drugs

digoxin

warfarin

pheytoin

tacrolimus

what generic drug is lanoxin (brand name)

digoxin (generic)(narrow tI)

what is the generic name for dilatin

phenyloin (narrow tI)

what is the generic name for coumadin

warfarin(narrow tI)

what is the generic name for prgraf astagaf

tacrolimus (narrow tI)

nsaids are _________

extensively protein plaism binding (over 90%)

benzodiazepines (drug class), what do the drugs names end with

am

list 5 opiods

fentanly, codeine, morphine, oxycodone, heroin

what drug class treats seizures

benzodiazepines

5 drugs that are well adsorbed by activated charcoal

acetlysalic acid, digitalis, benzodiazepines, tylenol, asa and ost nsaids

is tylenol an nsaid (hy/why nots)

no, does not treat inflammation or swelling

how to treat a tylenol overdose and what is its toxidrome

activaedt charcoal and NAC (iv,po)

t: ab pain

loss of apetite

nausea/vomiting

alchol generic name

ethanol/etoh

advil generic name

ibuprofen

hwo to treat asa overdose

activated charcoal

how to treat benzodiazepines overdose

activated charcoal

2 poorly adsorbed drugs by activated charcoal

ethanol

iron

what does metadoxine do

treats alcohol poisoning

induces alcohol dehydrogenase

advil toxidrome

confusion

tachycardia

tachypnea

hyperthermia

narcan generic name

naloxone

when is sodium bicarbonate used

in asa toxicty (ionizes acidic substances)

what does flumazenil do and

what receptor does it target

treats benzodiazepine toxicity (gaba receptor antagonist)

opiod toxidrome

bradypnea, bradycardia, somnolence, pupils constrict

xanax trade name

what drug class

alprazolam-

benzodiazepines

cocaine toxidrome

agitation, tremors

tachcardia/pnea

hyperthermia, pupils dilated

how does thc work vs cbd

t- cns and vital sign instability (hype)

c; moudlate the effect of the thc at receptors

how to treat a benzodiazepines overdose

activated charcoal

what drug class is digoxin under

cardiac

what is diphenhydramine

(benadryl) first rder antihistamine

what is chlorpherinamine

1st order antihistamine (in benylin

what is fexofendaine and in what brand name drug

2nd order antihistamine

allegra

what is loratadine and in what brand name drug

2nd order histamine

claritin

what is ceritizine and what brand name

2nd order histamine

reactine

what is desloratidine and in what brand name

aerius

2nd order antihis

what is patanol treating and generic name

olopatadine

toppical antihistamine for eye symptoms

what does nsaids stand for

non steroidal anti-inflammatories

what do nsaids inhibt

cox enxymes (1 and 2)

what type of drug celecoxib and what is its generic name

selective cox-2 inhibitor

celebrex

what is asa short for and where doe sit dissolve

acetlysalicylic acid

stomach

what is asa classified as (related to nsaids)

non-selective cox inhibitor

what is iburprofen (advil, motrin) classifeid as (relate to nsaids)

non-selective COX inhibitor

4 ibuprofen like drugs that are non-selective cox inhibitors

voltaren (diclofenac)

naproxen (aleve, naprosyns)

keterolac (toradol)

indomethacin

what do glucocorticoids that are administered do

high efficacy for tissue inflmmation

what type of drug is hydrocortisone and cortisone

glucocorticoids

what type of drug is predinisone and prednisolone

glucocorticoids

what type of drug is methylprednisolone and dexamethasone

glucocorticoids

what type of drug is singulair (montelukast)

leukotriene modifier (if allergen is EXPECTED- prophylaxis)

when is dexamethasone administered

• in analyphylaxis

• not immediate onset but long lasting inflammatory help and helps reduce discomfort later (hopefully wont reoccur)

what is the side effects of glucocorticoid hydrocortisone (topical)

minimal side effects

intranasal flonase generic name and class

fluticasone (glucocorticoid, min side effects tho)

3 ways gluticocorticoids relate to inflammation

prosatgaldin synthesis inhibition (COX 2)

histamine rease suppresion

suppresion of phagocytes and lymphocytes

what is mometasone

intanasal corticosteroid

what is budenosdie(rhinocort)

intranasal corticosteroid

what does the drug class brm do

inhibit pro-inflammatory cytokines (ex; interleukins and integrins)

infliximab drug class and fx

brm

anti-tnf blocker

adalimumab drug class and fx

brm

anti-tnf blocker

ustekinumab drug class

brm

what to dmards do

inhibit nucleotide synthesis

inhibit wbc synthesis

what drug class is methroxate and what is the brand name under

dmard

trexall

what drug class is azathioprine under and what is generic name

aza

dmards

dmards onset time

weeks

are aminosalicylates (5-asa) nsaids

yes

what is mesalamine (asacol) drug class and what doe sit do

aminosalicylates

nsaids w high specify to gi inflammation

ibd tx

what drug class is olsalazine (dipentum) under and what doe sit do

aminosalicylates

nsaids w high specify to gi inflammation

ibd tx

what drug class in sulfasalazine (salazopyrin)

aminosalicylates

how does sulfasalazine work

prodrug, metabolized in the colon and turns into

1 5 asa

2 sulfapyridine(dmards)

2 biologic drug classes

a4b7 integrin blocker

anti-TNF

what drug class does vedolizumab (entyvio) fall under

a4b7 intergin blocker

what drug class does infliximab (remicade) fall under

anti-tnf

what drug class does Adalimumab (humira) fall under

anti-tnf

what drug class are in controllers for asthma

glucocorticosteroids

what is pulmicort (budnoside)

glucocorticoid associated with maintenance asthma drugs

what is qvar (beclomethasone)

glucocorticoid associated with maintenance asthma drugs

what is flovent (fluticasone)

glucocorticoid associated with maintenance asthma drugs

what drug class is cromolyn (cromoglicic acid) under

mast cell stabilizer

what drug class helps with long term maintence (biologics)

anti- IgE antibody

omalizumab is it an anti-tnf

NO, these in long term biologic maintenace drug (xolair, anti-ige)

what drug class is xolair (omalizumab) under

anti-IgE antibody

multi year tx

asthma rescue drg classes (2)

beta 2 adrenergic agonist- potent and fast onset

anticholinergics- less potent, slower onset