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What are the 4 processes of respiration?
pulmonary ventilation
external respiration
gas transport
internal respiration
What is the equation for respiratory pressure?
intrapulmonary - atmospheric
What does a + respiratory pressure mean?
exhaling
What does a - respiratory pressure mean?
inhaling
What muscles contract in forced inhalation?
scalenes & pectoral minor
What muscles contract in forced exhalation?
abs & internal intercostals
What does IRV mean?
amt of air that can be inhaled past a normal breath
What does ERV mean?
amt of air that can be forcefully exhaled from the lungs after a normal breath
What does RV mean?
amt of air remaining in the lungs after a maximum exhalation
What does TV mean?
volume of air in & out during normal breaths
What does VC mean?
how much air you can move in & out
What does TLC mean?
VC+RV
What is the forced vital capacity test?
amt of air forcefully expelled following full inhale
What is Forced Expiratory Volume?
amt of air forcefully expelled during a set amt of time
What are some causes of restrictive disorders?
fibrosis, costal ossification, weakening of inspirational muscles
What is Dalton’s Law of Partial Pressure?
PP of a gas is proportional to the % of that gas in the mixture
What is Henry’s Law?
gas will dissolve into a liquid in proportion to its partial pressure
(higher pressure difference = more efficient)
What are the factors that influence external respiration?
pneumonia & emphysema
What is ventilation?
how much gas is in the alveoli
What is perfusion?
rate of blood flow in the alveoli
What happens to bronchioles when CO2 is high?
they dilate, leading to an increase in external respiration
What happens to pre-capillary sphincters when O2 is high?
They dilate, leading to an increase in blood flow to the respiratory membrane & external respiration
Why does pH shift matter?
CO2 causes a pH shift, decreasing oxygen affinity
What are the functions of the digestive system?
ingestion
mechanical breakdown
propulsion
chemical digestion
absorption
What does the mucosa layer contain?
lamina propria & muscularis propria
What does the submucosa contain?
esophageal glands —> mucous
What is the function of the muscularis externa?
propulsion & mixture
What does the serosa layer contain?
immune cells
What are the 2 phases of deglutition?
buccal phase
pharyngeal-esophageal phase
In the stomach, what are the 3 layers of the muscularis externa?
oblique
circular
longitudinal
What do parietal cells do?
produce HCl and the intrinsic factor (B12)
What do chief cells produce?
pepsinogen and lipase
What do enteroendocrine cells produce?
hormones
Where is gastrin produced?
G cells
What does gastrin do?
directly activates parietal cells and indirectly activates ECLs
What are the 3 phases of gastric juice production?
cephalic
gastric
intestinal
What does the small intestine do?
does the bulk part of digestion
Where is intestinal juice produced?
Intestinal Crypts
What cells have brush border enzymes?
enterocytes
What cells have antimicrobial compounds?
Paneth cells
What does the pancreas do?
contains enzymes that aid in digestion
What is the enzyme that breaks down proteins?
trypsin & chemotrypsin
What are the hormones used by the duodenum to regulation digestion?
CCK & Secretin
What is the function of the liver?
stores nutrients & produces bile
What is the function of the gallbladder?
stores bile & releases bile through bile duct
What are the two steps in absorption for carbs & proteins?
co-transport and facilitated diffusion
What are the steps in absorption of fat?
diffusion, reformation into triglycerides, and movement into the lymph
What other things are absorbed by the SI?
vitamins, electrolytes, & water
What anal sphincter is made of smooth muscle?
internal
What anal sphincter is made of skeletal muscle?
external
What does bacterial flora influence?
body weight, susceptibility to illness, & mood