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What 2 receptors do beta-blockers work on?
Beta-1 and Beta-2
Bisoprolol
- Beta-1 adrenoreptor antagonist
- Causes a blockade at the Beta-1 receptor preventing hormones such as adrenaline binding to and stimulating the receptor.
What condition are Beta-2 Adrenoreceptor Antagonists C/I in?
- Asthma & COPD
- They bind to Beta-2 receptors found in bronchial smooth muscle and induce bronchoconstriction, exacerbating symptoms of asthma.
S/Es of Bisoprolol
- Coldness at the extremities.
- Impotence/ED