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Last updated 9:03 PM on 5/2/25
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56 Terms

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Epidermis

The outermost layer of skin, characterized by actively growing cells and a protective keratinized top layer.

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Dermis

The layer of skin beneath the epidermis, composed of connective tissue, containing nerves, muscles, and glands.

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Subcutaneous

The innermost layer of skin, which contains fat cells.

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Keratinization

The process in which skin cells become filled with keratin and eventually die, contributing to skin's protective barrier.

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Sebaceous secretions

Oil produced by sebaceous glands that helps maintain skin's low pH, inhibiting microbial growth.

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Lysozymes

Antimicrobial enzymes found in sweat, tears, and saliva that help to inhibit microbial growth.

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Staphylococcus epidermidis

A bacterium that is part of normal skin flora, utilizing skin nutrients and producing antimicrobial substances.

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Propionibacterium acnes

A bacterium involved in acne development.

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Staphylococcus aureus

A pathogen that can cause skin infections and is often found in abnormal skin flora.

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Impetigo

A superficial skin infection characterized by peeling epidermis and pus-filled lesions, commonly caused by S. aureus.

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Cellulitis

A painful skin infection that involves the dermal and subcutaneous layers, treated with antibiotics.

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Scalded Skin Syndrome

A condition caused by S. aureus that results in widespread exfoliation of the skin and is serious in infants.

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MRSA

Methicillin-Resistant Staphylococcus aureus; a strain of S. aureus that is resistant to methicillin and poses treatment challenges.

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Necrotizing fasciitis

A rapid, invasive infection known as "flesh-eating bacteria," often requiring surgical intervention.

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Varicella-Zoster Virus

A herpesvirus that causes chickenpox and shingles.

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Chickenpox

A highly contagious childhood disease characterized by a rash; can have serious complications in adults.

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Shingles

Reactivation of the dormant chickenpox virus, usually in older adults or immunocompromised individuals.

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Lyme Disease

Vector-borne disease caused by Borrelia burgdorferi, primarily transmitted by ticks.

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Borrelia burgdorferi

A spirochete bacterium responsible for Lyme disease.

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Smallpox Virus

The first disease eradicated through vaccination; caused by Variola virus.

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Edward Jenner

The physician who developed the first smallpox vaccine.

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Vaccinia virus

The virus used in the smallpox vaccine, derived from cowpox.

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Gastric ulcers

Ulcers caused by Helicobacter pylori, a bacterium that can survive the acidic environment of the stomach.

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Exotoxin

A toxin secreted by bacteria, often causing damage to the host.

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Endotoxin

A toxic substance that is part of the bacterial cell wall and released upon destruction of the bacterium.

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Helicobacter pylori

A gram-negative bacterium that causes gastric ulcers and is associated with stomach cancer.

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Vibrio cholerae

A gram-negative bacterium that causes cholera, characterized by severe dehydration due to diarrhea.

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Cholera toxin

An enterotoxin produced by Vibrio cholerae, which disrupts intestinal function.

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Escherichia coli

Bacteria that can cause gastroenteritis; pathogenic strains can lead to severe diarrhea.

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Salmonella

Bacteria that can cause gastroenteritis and typhoid fever, often transmitted through contaminated food.

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Campylobacter jejuni

A gram-negative bacterium that is one of the most common causes of foodborne illness.

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Clostridium difficile

A gram-positive bacterium causing antibiotic-associated diarrhea and colitis.

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Rotavirus

A virus that causes viral gastroenteritis, particularly in children.

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norovirus

A virus common in outbreaks of food poisoning, especially on cruise ships.

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Food Poisoning

Illness caused by pre-formed toxins in contaminated food.

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Mucociliary escalator

A defense mechanism in the respiratory tract that removes pathogens through cilia movement.

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COVID-19

The disease caused by the novel coronavirus SARS-CoV-2.

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SARS-CoV-2

The virus responsible for COVID-19, a positive-stranded RNA virus.

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Influenza

An infectious disease caused by influenza viruses, characterized by respiratory symptoms.

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Pneumonia

Inflammation of the lungs, commonly caused by bacteria or viruses.

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Mycobacterium tuberculosis

The bacterium that causes tuberculosis; characterized by its acid-fastness and resistance to treatment.

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Bordetella pertussis

The bacterium that causes whooping cough, characterized by severe coughing spells.

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Rhinoviruses

The most common viruses responsible for the common cold.

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Genital Herpes

A sexually transmitted infection caused by herpes simplex viruses, leading to painful genital sores.

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Human Papillomavirus (HPV)

A common sexually transmitted virus that can lead to genital warts and cervical cancer.

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Zika virus

A virus transmitted primarily by mosquitoes, associated with birth defects when contracted during pregnancy.

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HIV

Human Immunodeficiency Virus, which causes AIDS and weakens the immune system.

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Highly Active Anti-Retroviral Therapy (HAART)

Effective treatment for HIV/AIDS that combines multiple antiretroviral drugs.

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Soil microbiome

The community of microorganisms found in soil, crucial for soil health and ecosystems.

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Biogeochemical cycles

Natural processes through which nutrients cycle in the environment, including carbon and nitrogen cycles.

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Mycorrhizae

Symbiotic association between fungi and plant roots, enhancing nutrient uptake.

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Nitrogen-Fixing bacteria

Bacteria such as Rhizobium that convert atmospheric nitrogen into a form usable by plants.

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Virulence factors

Molecules produced by pathogens that enhance their ability to cause disease.

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Pathogen recognition

The ability of an organism (e.g., plants) to identify and respond to microbial invaders.

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Phytoalexins

Antimicrobial compounds produced by plants in response to pathogen attack.

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Hypersensitive response

A rapid cell death response by plants to limit pathogen spread.