Coag tests

what is the purpose of the Anti-Xa assay

to monitor heparin therapy by measuring inhibition of factor Xa

what is the purpose of the D-dimer test

to detect fibrin degradation products and help rule out thrombosis (DVT, PE, DIC)

what is the purpose of dRVVT

to detect lupus anticoagulant by directly activating factor X

what is the purpose of a factor assay

to measure specific clotting factor activity and identify deficiencies

what is the purpose of the Bethesda assay

Confirm and quantify factor VIII inhibitors (specific factor inhibitors)

what is the purpose of the fibrinogen assay

measure functional fibrinogen levels and assess bleeding risk, DIC, or liver disease

what is the purpose of mixing studies

distinguish between factor deficiency and inhibitors

correction = factor deficiency

no correction = inhibitor

what is the purpose of the reptilase test

evaluate fibrinogen function and differentiate from heparin effect

NOT affected by heparin

what is the purpose of the silica clotting time (SCT) Staclot

detect lupus anticoagulant

what is the purpose of thrombin clotting time (TCT)

assess fibrinogen → fibrin conversion

detects heparin or fibrinogen abnormalities

what is the purpose of the urea clot solubility test

detect factor XIII deficiency (unstable clot dissolves)