Approved Drugs for Aquaculture

USFWS document 3rd ed. July 2020

chorionic gonadotropin - product name and supplier

Chorulon

chorionic gonadotropin - species

male and female brood finfish

chorionic gonadotropin - indication

aid in improving spawning function

chorionic gonadotropin - limitations

• IM injection

• inject up to three doses

  • total dosage not to exceed 25,000 IU in fish intended for human consumption

chorionic gonadotropin - withdrawl time

0 days

formalin external parasites - product name and supplier

• parasite -S

• formalin-F

• formacide-b

formalin external parasites - species

all finfish

formalin external parasites - indication

control of

• external protozoa

  • chilodonella

  • costia

  • epistylis

  • scyphidia

  • icthyophthirius

  • trichodina

• monogenetic trematodes

  • cleidodiscus

  • dactylogyrus

  • gyrodactylus

formalin (external parasites) - dosing (salmonids in tanks and raceways above 50 F)

up to 170 μL/L for up to 1 hr

formalin (external parasites) - dosing (salmonids in tanks and raceways below 50 F)

up to 250 μL/L for up to 1 hr

formalin (external parasites) - dosing (all other finfish)

up to 250 μL/L for up to 1hr

formalin (external parasites) - dosing (earthen ponds)

15–25 μL/L indefinitely

formalin (external parasites) - limitations

• do not subject water to below 40 F

• do not apply when

  • water is warmer than 80 F

  • there is a heavy phytoplanktoom bloom, or

  • DO is < 5 mg/L

formalin (external parasites) - how often to retreat

every 5–10d

formalin (external parasites) - which fish do not treat

striped bass

formalin (external parasites) - how to check for any unusual senstitivity

test on small number of fish from each lot

formalin (external parasites) - withdrawl time

0d

formalin (external parasites) - use with caution in what system

recirculating (impacts on biofilter)

formalin (external parasites, crustacean) - product name

same for fish

formalin (external parasites, crustacean) - species

penaeid shrimp

formalin (external parasites, crustacean) - indication

control

• protozoan parasites

  • Bodo

  • Epistylis

  • Zoothamnium

formalin (external parasites, crustacean) - limitations

same for fish

formalin (fungus) - species

all finfish eggs

formalin (fungus) - indication

control fungi (oomycete) from

• Saprolegniaceae

formalin (fungus) - recommended before treating entire lot?

test a small number of eggs

formalin (fungus, finfish) - product name

ONLY parasite-S

formalin (fungus, finfish) - species

freshwater-reared finfish

formalin (fungus, finfish) - indication

control mortality due to

• Saprolegniaceae

hydrogen peroxide - product name & supplier

35% perox-aid (syndel USA)

hydrogen peroxide (external bacteria) - species

• freshwater-reared salmonids

• freshwater-reared coolwater and warmwater finfish

hydrogen peroxide (external bacteria, freshwater-reared salmonides) - indications

control of mortality due to bacterial gill disease associated with Flavobacterium branchiophilum

hydrogen peroxide (external bacteria, freshwater-reared cool- and warmwater finfish) - indications

control of mortality due to external columnaris disease associated with Flavobacterium columnare

Hydrogen peroxide limitations

• preliminary testing on small group of fish first

• consider low end of dosing range or reducing water temp for initial treatments

• DO NOT USE IN

  • northern pike

  • paddlefish

  • pallid sturgeon fry

• CAUTION IN

  • walleye Sander vitreus

  • ornamental fish

hydrogen peroxide - withdrawl time

0 days

hydrogen peroxide (fungus) - species

• freshwater-reared

  • finfish eggs

  • coldwater finfish (all lifestages)

  • coolwater and warmwater fingerlings and adults

Hydrogen peroxide (fungus) - indication

control of mortality due to saprolegniasis

hydrogen peroxide (fungus) - limitations and comments

• careful monitor of tx on eggs - some strains of rainbow trout are sensitive during blastopore formation

• DO NOT TREAT of any age

  • northern pike Esox Lucius, or

  • paddlefish Polyodon spathula

  • Coolwater or warmwater fry

• CAUTION in

  • walleye Sander vitreus

  • ornamental fish

hydrogen peroxide (fungus) - withdrawl time

0 days

hydrogen peroxide (monogenean) - species

freshwater-reared salmonids

hydrogen peroxide (monogenean) - indication

control of Gyrodactylus spp.

Chloramine-T product name and supplier

Halamid Aqua (Syndel USA)

chloramine-T species

• freshwater-reared salmonids

• walleye

• freshwater-reared warmwater fish

chloraime-T species (Flavobacterium spp.) - species

freshwater-reared salmonids

chloramine-T (Flavobacterium columnare) - species

• walleye

• freshwater-reared warmwater finfish

chloramine-T indications

• control of mortality due to bacterial gill disease associated with Flavobacterium spp.

• control of mortality due to external columnaris disease associated with Flavobacterium columnare

cholarmine-T limitations and comments

• if used in recirculating system, bypass biofilter during tx and flushing

• walleye fingerlings more sensitive than fry

chloramine-T withdrawl time

0 days

oxytetracycline hydrochloride product name and supplier

• Pennox 343 (Pharmgate Animal Health)

• Tetroxy 343 (Bimeda)

oxytetracycline hydrochloride species

finfish fry and fingerlings

oxytetracycline hydrochloride indications

mark skeletal tissue

oxytetracycline hydrochloride - limitations and comments

• prescription product - licensed vet

• oxytet HCl will acidify water - maintain pH acceptable for fish by adding buffer

• monitor water quality and temperature