Innate Immunity Introduction

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Last updated 8:02 AM on 1/1/23
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13 Terms

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Phagocytosis
________: the process of destroying a particle by cells (cell eating)
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INF α
mononuclear, phagocytes
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INF β
fibroblast
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INF γ
mainly by T cells
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phagocytosis
the process of destroying a particle by cells (cell eating)
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ADCC
Antibody Dependent Cellular Cytotoxicity
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Innate immune response
natural inborn barriers against invasion by any foreign body
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Physiological barriers
Skin

Conjunctiva

Respiratory tract

Gastrointestinal tract

Genitaourinary tract
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Mechanisms
* Physiologic
* Humoral
* Cellular
* Inflammatory
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NK cells (cytotoxic)
* Large granular lymphocytes
* CD16 & CD56
* killing virus infected cells (tumor cells)
* (ADCC: Antibody Dependent Cellular Cytotoxicity)
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NK cell killer function
* apoptosis induction in infected and tumor cells
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Steps of phagocytosis:

1. Chemotaxis
2. Migrations
3. Attachment
4. Ingestion
5. Killing (digestion)
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phagocytosis
the process of destroying a particle by cells (cell eating)