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Ribosomes
Non-membrane organelles made of rRNA and protein; synthesize proteins based on mRNA. Found in all life, reflecting common ancestry.
Endomembrane system
Group of membrane-bound organelles (ER, Golgi, lysosomes, vacuoles, vesicles, nuclear envelope, plasma membrane) that modify, package, and transport molecules.
Rough ER
Endoplasmic reticulum with bound ribosomes; carries out protein synthesis and compartmentalizes the cell.
Smooth ER
Endoplasmic reticulum lacking ribosomes; functions in lipid synthesis and detoxification.
Golgi complex
Series of flattened membrane sacs that fold, modify, and package proteins for trafficking.
Mitochondria
Double-membrane organelles that perform aerobic cellular respiration; inner membrane folds (cristae) increase surface area for ATP synthesis.
Lysosomes
Membrane-enclosed sacs containing hydrolytic enzymes; digest material and play a role in apoptosis.
Vacuoles (plant)
Large central vacuole maintains turgor pressure through nutrient and water storage.
Vacuoles (animal)
Smaller and more plentiful than in plants; store cellular materials.
Chloroplasts
Double-membrane organelles found in plants and photosynthetic algae; site of photosynthesis.
Surface area-to-volume ratio
Ratio that affects exchange of nutrients, waste, and heat; smaller cells have higher SA/V and exchange more efficiently and bigger cells have smaller SA/V and are better suited for storage
Effect of size on metabolic rate
Smaller organisms typically have a higher metabolic rate per unit body mass than larger organisms.
Phospholipid bilayer orientation
Polar hydrophilic phosphate heads face the aqueous environment; nonpolar hydrophobic fatty acid tails face inward.
Embedded membrane proteins
Hydrophilic regions face cytosol or protein interior; hydrophobic regions interact with the fatty acid interior of the membrane.
Fluid mosaic model
Model describing the membrane as a fluid framework of phospholipids embedded with proteins, steroids, glycoproteins, and glycolipids that move laterally.
Selective permeability
Property of plasma membranes that results from a hydrophobic interior; allows some molecules to pass and not others.
Molecules that freely cross membrane
Small nonpolar molecules: N2, O2, CO2 freely cross; small polar uncharged molecules (H2O, NH3) cross in small amounts.
Cell wall function
Found in Bacteria, Archaea, Fungi, and plants; provides a structural boundary, permeability barrier, and protection from osmotic lysis.
Concentration gradient
Difference in solute concentration across a membrane; the basis for diffusion and transport.
Passive transport
Net movement of molecules from high to low concentration without metabolic energy input.
Active transport
Movement of molecules requiring direct energy input; can move solutes from low to high concentration.
Endocytosis
Cell engulfs large molecules by folding the plasma membrane inward, forming vesicles.
Exocytosis
Internal vesicles fuse with the plasma membrane to release large molecules from the cell.
Facilitated diffusion
Passive transport of charged ions or large polar molecules through transport or channel proteins down a concentration gradient.
Aquaporins
Membrane channel proteins that transport large quantities of water across membranes.
Hypotonic solution
Solution with a lower solute concentration than the cell; water moves into the cell.
Hypertonic solution
Solution with a higher solute concentration than the cell; water moves out of the cell.
Isotonic solution
Solution with equal solute concentration to the cell; no net water movement.
Osmosis
Movement of water from regions of high water potential to low water potential, or hypotonic to hypertonic.
Water potential (Ψ)
Sum of pressure potential (Ψp) and solute potential (Ψs); water flows from high to low Ψ.
Solute potential equation
Ψs = −iCRT (i = ionization constant; C = molar concentration; R = pressure constant; T = temperature in K).
Osmoregulation
Maintains water balance and allows organisms to control internal solute composition and water potential.
Sodium-potassium pump
Active transport protein using ATP to pump 3 Na+ out and 2 K+ in; helps maintain membrane potential.
Membrane compartmentalization
Internal membranes minimize competing interactions and increase surface area for reactions, enabling specialized functions.
Endosymbiotic theory
Mitochondria and chloroplasts evolved from once free-living prokaryotic cells via endosymbiosis.
Prokaryote vs eukaryote compartmentalization
Prokaryotes lack membrane-bound organelles but have specialized internal regions; eukaryotes have internal membranes that partition the cell.