Ionisable functional groups c3

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Last updated 1:09 PM on 5/2/26
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4 Terms

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What does low pKa mean?

Strong acid (greater dissociation)

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What does a high pKa mean?

Weaker acid (less dissociation)

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What are the rules with pKa, what can we determine with them?

if the ph is below the pka the acid group will be more than 50% protonated

if the ph is above the pka, the acid group will be more than 50% deprotonated

acids are charged at pH above their pka

bases are charged at Ph below their pka

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What does the pKa show?

The pKa is the pH at which the group is 50% ionized