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400 flashcards covering key concepts from the lecture on neuroscience, including auditory and visual systems, memory types, and relevant brain structures.
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Who demonstrated echolocation?
Daniel Kish
What is muscle tone associated with?
Extrapyramidal pathway
Define proprioception
Awareness of body position in space
What type of sleep does not change with age?
REM
what type of sleep does serotonin increase
SWS
What is the function of the dorsal parts of the spine?
Sensation
What is the function of the ventral parts of the spine?
Movement
What genes are activated by clock and cycle genes?
Clock and cycle genes turn on the production of PER and CRY genes.
Where are homuniculi located
Primary somatosensory cortex
What does stage of sleep relates to the lymphatic system?
SWS
What type of sleep does serotonin reduce?
REM
What is the function of the claustrum?
timekeeper
What is neural coupling as per Uri Hassan's research?
synchronization of brain waves
What two systems are synchronized for language processing?
Auditory and motor
What can hearing problems predict?
Dementia
What is sound defined as? A change in ______
air pressure
How is amplitude measured?
decibels
How is frequency measured?
Hertz
What is the function of the outer ear?
Collect sound
What is the role of the pinna in hearing?
Funnel sound
What does the ear canal do?
Carry sound to tympanic membrane.
What does the tympanic membrane do?
Vibrate
Function the middle ear?
Amplify or suppress sound
List the order of parts involved in the middle ear.
Tympanic membrane, malleus, incus, stapes, oval window
What are the three bones in the middle ear?
Malleus, incus, and stapes.
What is the function of the malleus?
Collect and focus sound
Function of the incus?
Connects malleus to stapes
What does the stapes do in the auditory pathway?
Push on the oval window
What is the first part involved in the auditory pathway?
Pinna
What does the tensor tympani muscle do?
suppress sound
What is the role of the stapedius muscle?
suppress sound
In which greater system part of the inner ear are the hair cells located?
cochlea
How does the oval window contribute to auditory perception?
Creates waves in cochlear fluid
What is the function of the organ of Corti?
Convert mechanical vibrations into electrical signals
Which part of the basilar membrane to high frequencies affect?
wide stiff base
Which part of the basilar membrane to low frequencies affect?
thin apex
What does temporal coding impact?
Neuron rate of firing
What does place coding impact?
Location of hair cells
Where is the most specific site where transduction occurs?
inner hair cells
What connects the stereocilia on hair cells?
tip links
What happens to ion channels in hair cells when they bend?
K and Ca ion channels opend
What physically distinguishes inner hair cells (IHCs)?
round and small
What is the main role of outer hair cells (OHCs)?
Amplify sound
What do the efferent projections that outer hair cells receive modify?
basilar membrane stiffness
What neurotransmitter is associated with outer hair cells?
Acetylcholine
Where is the cochlear nucleus?
Brainstem
What is the main role of the superior olivary nucleus?
sound localization
What does the inferior colliculi discriminate in auditory processing?
frequency and pitch
What is the location, role of medial geniculate nucleus (MGN)?
thalamus, gateway
What is the primary auditory cortex (A1) known as?
Herschel’s gyrus
What types of sound qualities can neurons react to in A1?
pitch changes, duration, and volume
What are two examples of sounds that the auditory cortex is specially tuned for?
footsteps and speech
What drives sound localization?
superior olivary nucleus
What does high intensity indicate about the localization of sound?
closer
How do cochlear implants stimulate the cochlea?
electrically
What is the high ringing caused by damaged hair cells that is linked with Parkinson’s and Alzheimer’s disease?
Tinnitus
What is the primary purpose of the vestibular system?
balance and spatial orientation
What stabilizes images during head movement?
vor
What two structure types are key to the vestibular system?
semicircular canals and otolith organs
What do semicircular canals detect?
rotational acceleration
What do otolith organs detect?
horizontal and vertical movmenet
what otolith organ detects horizontal movment?
utricle
What fluid fills the vestibular organs?
endolymph fluid
What is the first ion that flows into the hair cells when the stereocilia bend toward the kinocilium?
potassium
What is the tallest sterocilia in hair cells?
kinocilium
How does bending towards kinocilium affect hair cell activity, what NT is released?
opens calcium ion channels, glutamate
What cell stage occurs when sterocilia bend away from kinocilium, what happens to firing rate?
hyperpolarization, decreases
One side of your head’s hair cells will increase firing, while the other will decrease firing, allowing brain to compute direction and speed
push pull coding
What phenomenon explains directional detection in the vestibular system?
Push-pull coding allows one side to increase firing while the other decreases when detecting motion.
What do the hair cells experience even at rest?
baseline rate of fire
What disorder is related to dislodged calcium crystals in the vestibular system?
Vertigo
What causes motion sickness?
excessive vestibular excitation
What is the cause of Meniere’s disease?
excess endolymph fluid
What is the most common motion sickness treatment?
diazepam
Why does olfaction have a more direct pathway to the brain?
bypasses BBB
What part of the brain is olfaction heavily interconnected with?
hippocampus
What is the first part of the olfaction pathway (before #1)?
odorant
What is the site of transduction in the olfactory pathway?
cilia
What two parts does the cribiform plate separate?
nasal cavity and olfactory bulb
What does the olfactory bulb contain?
glomeruli
What is the function of mitral and tufted relay cells? Carry info from ___ to ___
bulb, brain
What areas does the olfactory tract project to?
olfactory cortex, amygdala, olfactory tubercule and hippocampus.
What produces new immature olfactory cells?
GBCs
How long is the lifespan of olfactory sensory neurons (OSNs)?
30-60 days
Glomeruli contain thousands of ____
OSNs
What is anosmia?
loss of smell
What drives the vomeronasal system in other mammals?
VNO
What is a goal of the vomeronasal system?
avoid inbreeding
Blind patients can still navigate and identify objects despite lacking conscious visual perception.
paradoxical sight
Name the first 3 parts of the visual pathway?
cornea, pupil, lens
What do ciliary muscles do?
change the shape of the lens
What protects the eye from UV light and refracts light into the eye?
Cornea
Where is sensory transduction located in the eye?
retina
What are the two types of photoreceptors in the eye?
rods and cones
Which photoreceptors operate in dim light and are insensitive to color?
Rods
What photoreceptor requires more light and enable color vision with high acuity.?
Cones
In the dark, neurotransmitters are released by photoreceptors at a ____ rate.
constant
Light ____ photoreceptor activity, causing _____ phase in cells, decreasing ____ release.
inhibits, hyperpolarization, glutamate
Where is visual acuity highest?
fovea
In which type of bipolar cell is glutamate inhibitory?
on center