Obstetric Pharmacology and Fetal Conditions

Vocabulary flashcards covering fetal abnormalities, uterotonic drugs like Oxytocin and Misoprostol, and tocolytic agents.

Chromosomal abnormalities

Conditions specifically noted in the lecture include abnormalities of chromosomes $21$, $18$, and $13$.

Fetal akinesia

A condition characterized by the absence of swallowing in the fetus.

Twin-Twin transfusion

A specific condition listed alongside chromosomal and fetal abnormalities.

Oxytocin

A synthetic hormone that acts on the uterus to increase contractions ($++cx$); it is used for the induction of labor.

Side effects of Oxytocin

Includes hypotension, reflex tachycardia, water retention, neonatal jaundice, uterine rupture, and fetal hypoxia.

Uterotonics

A category of medications, including Oxytocin and Misoprostol, used to stimulate uterine contractions.

Misoprostol

A $PGE_1$ analog used to protect against chronic NSAID use and reduce gastric acid; it is used off-label for induction because it acts on the uterus.

Indomethacin (Indocid)

A COX inhibitor (NSAID) used as a $1^{st}$ line tocolytic agent.

Atosiban (Tractocile)

An oxytocin-receptor antagonist used as a tocolytic to inhibit uterine contractions.

Tocolytics

A class of medications used to suppress premature labor, with agents such as Indomethacin and Atosiban mentioned.