Cystic Fibrosis Brand/Generic

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Last updated 9:15 PM on 6/12/26
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12 Terms

1
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What is the order of physiotherapy and inhaled therapies for CF?

  1. inhaled bronchodilator (albuterol) - open airways

  2. hypertonic saline - mobilize mucus

  3. dornase alfa - thin mucus

  4. chest physiotherapy - mobilize to increase clearance

  5. inhaled antibiotics - decrease infection

2
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hypertonic saline

HyperSal, PulmoSal

3
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dornase alfa

Pulmozyme

4
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tobramycin

TOBI, TOBI Podhaler

5
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aztreonam

Cayston

6
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azithromycin

Zithromax

7
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pancrelipase

Creon, Viokace, Zenpep

8
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ivacaftor

Malydeco

CFTR modulator. increases time that channels are open

NOT approved for F508del mutation

9
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lumacaftor/ivacaftor

Okambi

corrects CFTR folding. increases CFTR at cell surface. also increases channel open time

approved for F508del mutation

10
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tezacaftor/ivacaftor

Symdeko

corrects CFTR folding. increases CFTR at cell surface. also increases channel open time

approved for F508del mutation

11
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elexacaftor/tezacaftor/ivacaftor

Trikafta

corrects CFTR folding. increases CFTR at cell surface. also increases channel open time

approved for F508del mutation

12
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vanzacaftor/tezacaftor/deutivacaftor

Alyftrek

corrects CFTR folding. increases CFTR at cell surface. also increases channel open time

approved for F508del mutation