VIT E

Sure

• coined the name Vitamin E; now known to be a variety of tocopherols.

What are the several tocopherols

• α, β, γ, δ

• Alpha is the most active and common form

How are Tocopherols measured?

• 1 IU = 1 mg of synthetic D,L-α-tocopheryl acetate (is the international standard).

• 1 mg α-tocopherol = 1.1 IU

• 1 mg D- α-tocopheryl acetate = 1.36 IU

• 1 mg D-α-tocopherol = 1.49 IU

What are the different functions of Vit E

• Natural antioxidant

• Essential for reproduction in rat, pig, and poultry

• Functions are closely related to selenium

• Blocks lipid peroxidation and the formation of free radicals in the cell membrane

What are the different diseases of vitamin E deficiencies?

• Muscular Dystrophy

• Muscle weakness (paralysis, degeneration, creatine, excretion)

• Stiff lambs disease in sheep

• White muscle disease in calves

• Exudative Diathesis

• Gizzard erosion in turkeys

• Heart muscle damage

• Nutritional Encephalomalacia

How can you cure stiff lambs disease in sheep?

• Tocopherols

How can you cure white muscle disease in calves?

• Selenium

What is Exudative diathesis?

• a hemorrhagic disease of chicks - prevented by Vitamin E. Responds also to Se

How is Gizzard erosion in turkeys caused?

• Breakdown of smooth muscle

What is nutritional encephalomalacia?

• Happens in chicks

• Known as crazy chick disease

What are tocopherols?

1. α form most active

2. Tocopherols are extremely resistant to heat but are easily oxidized. They rancid fats easily & destroy the vitamin

3. Vit. E protects certain dietary constituents from oxidative destruction such as carotene in intestines

4. In body tissues; it also prevents the formation of peroxides from the unsaturated fatty acids that would destroy structural integrity of cells.