Antibiotics Large Ani

Beta Lactam

cidial

Breaks down cell wall, G+

excrete via kidneys

doesnt work w bacteria that have beta lactamase

DONT USE WITH MYCOPLASMA

ex: penicillin, amoxicillin, cephalosporins

Tetracyclines

static, broad

Inhibit bac prot synth; g+/-, fastidious and g- enteric

variable against mycoplasma

concentrate in inflammed areas (pH)

antagonistic to beta lactams

ex: oxytetracycline, chlortetracycline, doxy, tetracycline

Aminoglycosides

cidial

inhib prot synth, g- enteric and fasidious

used with penicillin

streptomyocin used for wooden tongue

ex: streptomyocin, gentamycin, neomycin

Sulfonamides

static, broad

inhib bacterial folate synthesis, g+/-, enteric and fastidious, NOT MYCOPLASMA

inhibited by pus!

ex: TMPS, sulfadiazine, sulfapyridine

Florfenicols

static, broad

disrupt bac prot synth, g+/-, enteric and fastidious AND MYCOPLASMAS

penetrates joints, balls, lungs, BBB

ex: florfenicol, chloraphenicol, thaimphenicol

Macrolides

static

inhib prot synth; g+/-, fastidious, mycoplasma, BUT NOT ENTERIC!

concentrate in inflamm, long duration, used in pneumonia and lameness

ex: ngamithromycin, tilmicosin, tylosin

Lincosamides

static

inhib prot synth; g+, g- fastidious and mycoplasmas (NOT ENTERIC)

good against anaerobic bac

ex: lincomycin, clindamycin, pirlymycin

Fluroquinolones

HP-CIA (AVOID USE, NOT FIRST LINE)

cidal, broad

inhib bac DNA synth, g+/-, enteric, fastidious AND MYCOPLASMA

ex: marbofloxacin, enrofloxacin, norfloxacin