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What is Intracellular fluid (ICF)?
fluid within cells
What is Extracellular fluid (ECF) and what are the two components of it?
fluid outside cells, interstitial fluid and plasma
The cell membrane separates what?
intercellular fluid from surrounding interstitial fluid
What divides interstitial fluid from blood plasma?
blood vessel walls
What are three ways we gain water and what are three ways we lose water?
Gain: ingested fluids, ingested foods, and metabolic water
Lose: Kidneys (Urine), Skin (sweat), Lungs (vapor), GI tract (feces)
What regulates the gain of water?
thirst center of hypothalamus
What regulates loss of water?
ADH-reabsorbs water, Angiotensin II and Aldosterone- reabsorbs Na and Cl, ANP-excretes Na and CL
What is the most common reason for change in osmolarity?
Na
An increase in osmolarity of interstitial fluid will cause cells to
shrink because what is being drawn out
A decrease in osmolarity of interstitial fluid will cause cells to
swell because it draws fluid in
Cations are
positive
Anions are
negative
Is sodium a cation or anion? where is it most abundant? what is it needed for?
Cation, ECF, needed for action potentials in muscle and nerve tissue
Chloride is a cation or anion? where is it most abundant?
Anion, ECF
Potassium is a cation or anion? Where is it most abundant?
Cation, ICF
Bicarbonate is a cation or anion? Where is it abundant? when does the concentration decrease?
Anion, ECF, when Co2 is exhaled
Calcium is a cation or anion? Where is it most abundant?
Cation, the body because of bones
Phosphate is a cation or anion? What does it act as?
Anion, an important buffer inside the cell
Magnesium is a cation or anion? Where is it found? What is it needed for?
Cation, in bone, for neuromuscular activity, cofactor for enzymes
Acidosis happens when the pH
falls below 7.35
Alkolosis happens when the pH
rises above 7.45
Respiratory compensation is
the use of the respiratory system to correct pH imbalance
Renal compensation is
the use of kidneys to secrete H+, or reabsorb HCo3 to correct pH imbalance
Respiratory Acidosis is a decrease of _____ and a increase in _____
pH, Co2
Respiratory Alkalosis is an increase in ___ and a decrease in ____
pH, Co2
Metabolic Alkalosis is a increase in ___ and a increase in ____
pH, HCo3
Metabolic Acidosis is a decrease in ____ and an decrease in ____
pH, HCo3
A decrease in pH will result in (respiratory)
a faster breathing rate
An increase in pH will result in (respiratory)
a slower breathing rate
What are the three types of buffer systems in acid-base balance?
Protein buffer system, carbonic acid bicarbonate buffer system, and phosphate buffer system
Which buffer system works in both ICF and ECF?
Protein buffer system
Which buffer system act on the ECF only
Carbonic acid bicarbonate buffer system
Which buffer system acts predominately on the ICF
Phosphate buffer system
More Co2 =
more acidic
Less Co2=
more basic
In the protein buffer system, it contains a COOH and -NH2. When pH rises what releases what? When the pH falls what does what
Rise: COOH releases H
Fall: NH2 binds to H