Lab 10 Multistep Synthesis Sequence: An Aldol Condensation, A Michael Addition

what is a condensation reaction

reaction that combines two molecules and removes some water or alcohol

what happens with the aldol condensation

the alpha hydrogen of the acetone is deprotonated by the ethanol. The the deouble bond from the oxygen shift down and makes a nucleophilic double bond to that carbon. Then the nucleophile attacks the carbonyl carbon from the p-anisaldehyde. The electrons will get pushed up on the carbonyl of the p-anisaldehyde and then get turned into an alcohol. This happens twice on both alpha carbons but the it will get dehydrate, so the H from the alpha carbon will get eliminated and kick off the OH.

what happens with michael addition

the alpha carbons of 2 molecules of dimethyl malonate will attach to both beta carbons of the dianisalacetone. The alpha carbon will be deprotonates using ethanol

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