Miscellaneous drugs

Imitrex generic name?

Sumatriptan

Sumatriptan brand name(s)?

Imitrex

Sumatriptan drug class?

Serotonin 5-HT Receptor Agonist

Sumatriptan indication(s)?

migraines; cluster headaches

Sumatriptan MOA?

selective serotonin agonist that causes vasoconstriction that reduces neurogenic inflammation

Sumatriptan adverse effects?

tingling, lightheadedness, muscle weakness, dizziness, drowsiness

Sumatriptan renal dose adjustment?

N

Sumatriptan hepatic dose adjustment?

Y

Maxalt generic name?

Rizatriptan

Rizatriptan brand name(s)?

Maxalt

Rizatriptan drug class?

Serotonin 5-HT Receptor Agonist

Rizatriptan indication(s)?

migraines

Rizatriptan MOA?

selective serotonin agonist that causes vasoconstriction that reduces neurogenic inflammation

Rizatriptan adverse effects?

tingling, lightheadedness, muscle weakness, dizziness, drowsiness

Rizatriptan renal dose adjustment?

N

Rizatriptan hepatic dose adjustment?

N

Xyzal generic name?

Levocetirizine

Levocetirizine brand name(s)?

Xyzal

Levocetirizine drug class?

Antihistamine (second generation)

Levocetirizine indication(s)?

Allergic rhinitis; Urticaria

Levocetirizine MOA?

selectively antagonizes peripheral histamine H1-receptors

Levocetirizine adverse effects?

Drowsiness, fatigue, headache

Levocetirizine renal dose adjustment?

Y

Levocetirizine hepatic dose adjustment?

N

Claritin generic name?

Loratadine

Loratadine brand name(s)?

Claritin

Loratadine drug class?

Antihistamine (second generation)

Loratadine indication(s)?

Allergic rhinitis; Urticaria

Loratadine MOA?

selectively antagonizes peripheral histamine H1-receptors

Loratadine adverse effects?

Drowsiness, fatigue, headache

Loratadine renal dose adjustment?

Y

Loratadine hepatic dose adjustment?

N

Atarax / Vistaril generic name?

Hydroxyzine

Hydroxyzine brand name(s)?

Atarax; Vistaril

Hydroxyzine drug class?

First generation antihistamine

Hydroxyzine indication(s)?

Anxiety; Pruritis

Hydroxyzine MOA?

antagonizes H1-receptors; has additional action at dopaminergic, muscarinic, and serotonergic (5HT2) receptors

Hydroxyzine adverse effects?

Drowsiness, dry mouth

Hydroxyzine renal dose adjustment?

Y

Hydroxyzine hepatic dose adjustment?

N

Kenalog / Nasacort generic name?

Triamcinolone

Triamcinolone brand name(s)?

Kenalog (topical); Nasacort (nasal)

Triamcinolone drug class?

Corticosteroid

Triamcinolone indication(s)?

Dermatitis (topical); Allergic rhinitis (nasal)

Triamcinolone MOA?

decreases chemical mediators of inflammation by inducing phospholipase A2 (PLA2) inhibitory proteins and inhibiting arachidonic acid release resulting in anti-inflammatory, antipruritic, and vasoconstrictive effects

Triamcinolone adverse effects?

Local burning, itching, skin atrophy, secondary infection

Triamcinolone renal dose adjustment?

N

Triamcinolone hepatic dose adjustment?

N

Anusol-HC / Proctosol-HC generic name?

Hydrocortisone (topical)

Hydrocortisone (topical) brand name(s)?

Anusol-HC; Proctosol-HC

Hydrocortisone (topical) drug class?

Corticosteroid

Hydrocortisone (topical) indication(s)?

Pruritis; Dermatitis; Hemorrhoids; Ulcerative colitis

Hydrocortisone (topical) MOA?

decreases chemical mediators of inflammation by inducing phospholipase A2 (PLA2) inhibitory proteins and inhibiting arachidonic acid release resulting in anti-inflammatory, antipruritic, and vasoconstrictive effects

Hydrocortisone (topical) adverse effects?

Local burning, itching, skin atrophy, secondary infection

Hydrocortisone (topical) renal dose adjustment?

N

Hydrocortisone (topical) hepatic dose adjustment?

N

Temovate / Impoyz generic name?

Clobetasol (topical)

Clobetasol (topical) brand name(s)?

Temovate; Impoyz

Clobetasol (topical) drug class?

Corticosteroid

Clobetasol (topical) indication(s)?

Psoriasis; Dermatoses

Clobetasol (topical) MOA?

decreases chemical mediators of inflammation by inducing phospholipase A2 (PLA2) inhibitory proteins and inhibiting arachidonic acid release resulting in anti-inflammatory, antipruritic, and vasoconstrictive effects

Clobetasol (topical) adverse effects?

Local burning, itching, skin atrophy, secondary infection

Clobetasol (topical) renal dose adjustment?

N

Clobetasol (topical) hepatic dose adjustment?

N