Cattle Antibiotics Study Guide

Comprehensive practice flashcards covering cattle antibiotics, including their classification, spectrum of activity, mode of action, and penetration across physiological barriers based on lecture notes.

How is Amoxicillin classified in terms of bacterial action and mode of action?

It is bactericidal ($\text{CIDAL}$) and works by causing damage to the cell wall.

How does the penetration capability of Amoxicillin compare to Amphenicols?

Amoxicillin has $\text{POOR}$ penetration across difficult barriers, while Amphenicols have $\text{EXCELLENT}$ penetration.

Which antibiotic is specifically noted for its $\text{+++}$ activity against Penicillinase-producing Staphs?

Cloxacillin (and also Amoxiclav).

What are the common licensed products for Amoxiclav?

Injection, Oral Tablets, and Udder applications.

Which antibiotics listed are classified as $\text{STATIC}$ (bacteriostatic)?

Tetracyclines, Amphenicols, Macrolides, and Lincosamides.

What is the mode of action for TMPS?

Inhibit DNA Activity (nucleic acids).

Which Gram-negative aerobic bacteria are listed as examples in the notes?

E coli, Salmonella, Proteus, Pseudomonas, Pasteurella, Mannheimia, Leptospira, and Campylobacter.

According to the transcript, which group of Cephalosporins has $\text{NONE LICENSED IN FARM SPECIES}$?

Cephalosporins Generation 2.

What are the five 'difficult barriers' mentioned regarding antibiotic penetration?

Brain, Eye, Prostate, Blood/Milk, and Bronchus.

Which antibiotics are characterized as having $\text{GOOD}$ penetration across difficult barriers?

TMPS, Macrolides, and Tetracyclines.

What is the specific mode of action for Fluoroquinolones?

Inhibit DNA Activity (gyrase).

Which 'Atypical' bacteria are susceptible to Tetracyclines?

Rickettsia, Mycoplasma (with some resistance for Mycoplasma bovis), and Chlamydia.

How effective are Aminoglycosides against Gram positive aerobes according to the table?

They are rated as $-$ (Bad).

Which antibiotics have $\text{EXCELLENT}$ penetration across difficult barriers?

Amphenicols and Fluoroquinolones.

Name the primary mode of action for Macrolides and Lincosamides.

Interfere With Protein Synthesis (required for bacterial growth).

Which bacteria are classified as Obligate Anaerobes in the transcript?

Clostridium, Actinomyces, Bacteroides, Fusobacterium, D nodosus, and Treponemes.

What is the spectrum of activity for Cephalosporins Generation 4 against Gram positive aerobes?

$\text{+++}$ (Excellent).

Which antibiotics are NOT effective against Mycoplasma according to the 'Atypical Bacteria' notes?

TMPS and Beta Lactams.

What is the mode of action for Aminoglycosides?

Interfere With Protein Synthesis and Damage Cell wall.

Identify four examples of Gram Positive Aerobic Bacteria from the transcript.

Streptococcus, Staphylococcus, Enterococcus, Listeria, Corynebacteria, and Trueperella.