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Describe the cellular differences between developed follicles
Primordial: contains “follicular cells”
Primary: Contains granulosa cells
Secondary: Contains theca + granulosa cells
Tertiary: Antrum + theca cells + granulosa cells
What is the earliest stage a follicle can begin producing estrogen?
Secondary follicle
Need both theca and granulosa cells
What are the three phases of the ovarian cycle?
Follicular phase
Ovulation
Luteal phase
What occurs during the follicular phase of the ovarian cycle?
Proliferation of granulosa + theca cells
Antrum formation
Estradiol formation
What do theca cells produce? Describe the process. What hormone is required to facilitate this process?
Theca cells use LH (luteinizing hormone) to convert cholesterol to progesterone
Progesterone is then converted to androstenedione
What do granulosa cells produce? Describe the process. What hormone is required to facilitate this process?
Granulosa cells convert androstenedione to testosterone
FSH (follicle-stimulating hormone) is then used to convert testosterone to estradiol
What occurs during ovulation?
Follicle ruptures; wall of follicle is broken down by proteases/collagenases/prostaglandins
ovum released into abdominal cavity
What occurs during the luteal phase of the ovarian cycle?
Follicular wall turns into the corpus luteum (secretes estrogen & progesterone and relaxin/inhibin)
T/F: The stratum basalis replaces the stratum functionalis after menstruation
True
What are the phases of the uterine cycle? What happens in each phase?
Menses (shedding of S.F.) (~5 days)
Proliferative phase (regrowing S.F.) (~8-10 days)
Secretory phase (secretion of mucus via estrogen/progesterone to prep for potential implantation) (after ovulation - day 28)
What hormone is released by a developing embryo to the mother? What does this do?
hCG (human chorionic gonadotropin)
Discourages dissolution of the corpus luteum to support pregnancy