Osteoporosis - Pathophysiology Overview

These flashcards cover key terms and concepts related to osteoporosis as discussed in the lecture.

Osteoporosis

Also known as brittle bone disease, it is a common bone disease affecting older adults, characterized by an imbalance in the bone remodeling process.

Bone remodeling

The process involving bone resorption by osteoclasts and bone formation by osteoblasts.

Osteoclasts

Cells that break down bone tissue, leading to bone resorption.

Osteoblasts

Cells responsible for bone formation.

Estrogen

A hormone that aids bone growth; its loss during menopause is a primary cause of osteoporosis in women.

Kyphosis

A condition characterized by an exaggerated curvature of the spine, which can occur due to osteoporosis.

Vitamin D

A nutrient essential for calcium absorption; a deficiency can contribute to osteoporosis.

Fractures

Common sign of osteoporosis due to brittle bones, resulting in more frequent breaks.

Clinical manifestations

Signs and symptoms of a disease; in osteoporosis, includes fractures, back pain, and loss of height.

Etiology

The study of causation or origin of diseases; in osteoporosis, a major cause is the decrease in estrogen.