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Oxidation
Loss of electrons from a substance.
Reduction
Gain of electrons by a substance.
Oxidized species
Molecules that lose electrons in a redox reaction.
Reduced species
Molecules that gain electrons in a redox reaction.
Glycolysis
The breakdown of glucose to pyruvate, occurring in the cytoplasm of all cells.
Fermentation
The metabolic process that regenerates NAD⁺ in the absence of oxygen.
Pyruvate oxidation
Process where pyruvate enters the mitochondria and is converted to acetyl-CoA.
Electron Transport Chain (ETC)
A series of protein complexes located in the inner mitochondrial membrane that transfer electrons.
Acetyl-CoA
A key metabolic intermediate that enters the citric acid cycle.
Chemiosmosis
The movement of hydrogen ions across a membrane to generate ATP.
Anaerobic respiration
Respiration that uses an electron transport chain with a final electron acceptor other than oxygen.
Deamination
The process of removing amino groups from amino acids.
Beta oxidation
The metabolic process of breaking down fatty acids into acetyl-CoA units.
Proton-motive force
The potential energy stored in the form of a proton gradient across a membrane.
NADH
Electron carrier that donates electrons to the electron transport chain.
FADH₂
Another electron carrier that donates electrons to the electron transport chain.
ATP Synthase
Enzyme that produces ATP from ADP and inorganic phosphate through chemiosmosis.
Citric Acid Cycle
A series of chemical reactions used by all aerobic organisms to generate energy.
Methane (in methanogens)
A byproduct generated during anaerobic respiration when CO₂ is used as an electron acceptor.
ATP production collapse
Occurs when pyruvate dehydrogenase is inhibited, halting energy production.
Oxidized NAD+
Forms when NADH transfers electrons during cellular respiration.
Alcohol fermentation
The process where pyruvate is converted to acetaldehyde and then to ethanol.
Lactic acid fermentation
The process where pyruvate is directly reduced to lactate by NADH.