exam 3

What is the antibiotic that goes with Bacillus subtilis

Bacitracin

What is the antibiotic that goes with Paenibacillus polymyxa

Polymyxin

What is the antibiotic that goes with Streptomyces nodosus

Amphotericin B

What is the antibiotic that goes with Streptomyces venezuelae

chloramphenicol

What is the antibiotic that goes with Streptomyces aureofaciens

chlortetracycline and tetracycline

What is the antibiotic that goes with Streptomyces fradiae

neomycin

What is the antibiotic that goes with Streptomyces griseus

streptomycin

What is the antibiotic that goes with Saccharopolyspora erythraea

Erythromycin

What is the antibiotic that goes with Micromonospora purpurea

gentamicin

Which microorganisms are considered fungi

Cephalosporium spp,c, penicillium chrysogenum Penicillium griseofulvum

What is the antibiotic that goes with Cephalosporium spp

cephalothin

What is the antibiotic that goes with penicillium griseofulvum

griseofulvin

What is the antibiotic that goes with penicillium chrysogenum

penicillin

Narrow spectrum of microbial

drugs that affect a narrow range of microbial types

broad-spectrum antibiotics

affect a board range of gram-neg or gram-pos

superinfection

overgrowth (flourish) of an opportunistic pathogen when the normal microbiota are disrupted typically due to antibiotic use

examples of superinfections

Candida albicans,clostridium difficile

example of bactericidal

Penicillin, cephalosporins

example of bacteriostatic

tetracyclines

explain inhibiting cell wall synthesis

safe and effective but still have side effects

example inhibiting cell wall synthesis

penicillin

explain inhibiting protein synthesis

target bacterial 70S ribosomes, has side effects

example inhibiting protein synthesis

Chloramphenicol, erythromycin, streotmycin,tetacyclines

explain injuring the plasma membrane

Polypeptide antibiotics change membrane permeability, antifungal drugs combine with membrane sterols and have side effects

example injuring the plasma membrane

polymyxin B

explain inhibiting nucleic acid synthesis

can have side effects

What are the two drugs that inhibiting nucleic acid synthesis

quinolones and rifampin

quinolones

block topoisomerase (interferes with DNA replication)

rifampin

block RNA polymerase (interferes with transcription)

explain the synthesis of essential metabolites

antimetabolites compete with normal substrates for an enzyme and has some effects

examples of synthesis of essential metabolites

sulfanilamide- competes with para-aminobenzoic acid (PABA), stops the synthesis of folic acid

what does penicillin contain

a beta-lacctam ring

what does the ring do

prevents cross-linking of peptidoglycan interfering with cell wall construction

What are penicilinase-ressitance penicillins

methicillin and oxacillin

what are broad-spectrum oenicillin

amoxiccillin/clavaulanet

Penicillins plus B-lactamase inhibitors

clavulanic acid, a noncompetitive inhibitor of penicillinase